The major salivary glands consist of the parotid, the submandibular, and the sublingual glands. Under the control of the parasympathetic nervous system, the major salivary glands are responsible for the principal portion of saliva produced, which can be as much as 1.5 liters per day. The minor salivary glands of the oral cavity, pharynx, and upper airways contribute only a small percentage of t...

The present study was aimed to elucidate gross, histomorphological and histochemical status in parotid salivary gland of buffalo during neonatal life. The study was carried out on parotid salivary gland of eighteen buffalo neonates. These neonates were categorized into three groups based on their age, viz., Group-1: <1 month; Group-2: between1-2 months and Group-3: between 2-3 months. Macroscop...

INTRODUCTION Radiotherapy of nasopharyngeal carcinoma patients with parapharyngeal space (PPS) involvement may deliver high dose to the parotid gland. This study evaluated parotid gland changes during and up to 3 months after radiotherapy. METHODS Kilovoltage computed tomography (CT) scans of head and neck region of 39 nasopharyngeal carcinoma patients with PPS involvement were performed at p...

The murine parotid secretory protein (PSP) gene is expressed selectively at high levels in parotid and sublingual salivary glands. Previously, the transcriptional activity of a PSP mini-gene, called Lama, was shown to be dependent on a 1.5 kb region located 3 kb upstream of the transcription start site. Here, functional studies in transgenic mice demonstrate that this proximal regulatory region...

The goal of this study was to evaluate the actual anatomical and dosimetric changes of parotid glands in nasopharyngeal carcinoma patients during intensity modulated radiation therapy. With helical tomotherapy, its planning system, and adaptive software, weekly anatomical and dosimetric changes of parotid glands in 35 NPC patients were evaluated. Interweekly parotid volume varied significantly ...

The initial presentation of a cholangiocarcinoma (CC) as trismus due to metastasis to the parotid gland is extremely rare and no previous reports have been found in the literature. A 29-year-old woman presented trismus that initiated 2 months before admission, just after superior left third molar extraction. Physical examination revealed severe trismus and a mass in the parotid gland. Computed ...

We aimed to evaluate the efficacy of combination of propranolol and sclerotherapy in treating parotid hemangiomas. Twenty-six parotid hemangiomas patients were subjected to combined treatment from January 2009 and June 2014. The effects of the therapy modality were evaluated. Nineteen patients were females and 7 were males. The median age of treatment initiation was 4.96 months. Twelve lesions ...

DE-DIFFERENTIATION OF PAROTID ACINAR CELLS IN VITRO Andrew S. Currie July 16, 2010 Background: When rat salivary gland cells are cultured in vitro, they dedifferentiate within 24 h. Hypothesis: Growth factors will prevent de-differentiation of primary cultures of parotid gland cells, and they will induce differentiation of ParC5 cells. DNA methylation drives de-differentiation and the loss of e...

BACKGROUND AND PURPOSE Weak or absent CT enhancement in pleomorphic adenomas of the parotid gland has been observed immediately after i.v. contrast administration. This feature can result in poor lesion conspicuity relative to both normal parotid tissue and other parotid abnormalities. The purpose of this study was to document the delayed CT enhancement characteristics of parotid pleomorphic ad...

BACKGROUND A modified Blair's incision or standard facelift incision is recommended to remove tumors in the accessory parotid gland. These incisions frequently result in long and visible scars. Therefore, the authors have introduced an endoscopic approach via a small preauricular incision to achieve excision of benign tumors in the accessory parotid gland. METHODS The endoscopic surgical tech...