نتایج جستجو برای: paricalcitol
تعداد نتایج: 349 فیلتر نتایج به سال:
The vitamin D hormone system has significant skeletal and extra-skeletal effects. Vitamin D receptor occurs in different tissues, and several cells other than renal cells are able to locally produce active vitamin D, which is responsible for transcriptional control of hundreds of genes related to its pleiotropic effects. There is increasing evidence relating vitamin D to development and course ...
SU424. World Congress of Nephrology 2011. Vancouver, Canada.48. Tan X, Wen X, Liu Y: Paricalcitol inhibits renal inflammation by promotingvitamin D receptor-mediated sequestration of NF-kappaB signaling. J AmSoc Nephrol 2008, 19(9):1741-1752. 49. Gamboa JL, Pretorius M, Todd-Tzanetos DR, Luther JM, Yu C, Ikizler TA,Brown NJ. Comparative effects of angiotensin-converting enzyme
Albeit based on robust methods, the study by Dick de Zeeuw and colleagues (Nov 6, p 2010) raises several concerns. First, little attention is given to the fact that the primary endpoint— ie, the eff ect of the vitamin D receptor activator (VDRA) on urinary albuminto-creatinine ratio (UACR)—is actually negative. The positive results on secondary endpoints should thus be used only to generate new...
Excessive lymphangiogenesis is associated with cancer progression and renal disease. Attenuation of lymphangiogenesis might represent a novel strategy to target disease progression although clinically approved anti-lymphangiogenic drugs are not available yet. VitaminD(VitD)-deficiency is associated with increased cancer risk and chronic kidney disease. Presently, effects of VitD on lymphangioge...
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