Forebrain activation patterns in normal and spinal-injured Sprague-Dawley (SD) rats were determined by measuring regional cerebral blood flow as an indicator of neuronal activity. Data are compared to our previously published findings from normal and spinal-injured Long-Evans (LE) rats and reveal a striking degree of overlap, as well as differences, between strains in the basal (unstimulated) f...

Abstract We examined the activities of serotonin (5-HT) neurons in dorsal raphe nucleus (DRN) and corticotropin-releasing factor (CRF) hypothalamic paraventricular (PVN) during acute treadmill running at different speeds (control, low, high) durations (15, 30, 60 min) male Wistar rats using c-Fos/5-HT or CRF immunohistochemistry. also performed elevated plus maze test (EPM) forced swim (FST) af...

Abstract Lowered glucose availability, sensed by the hindbrain, has been suggested to enhance gluconeogenesis and food intake as well suppress reproductive function. In fact, our previous histological in vitro studies suggest that hindbrain ependymal cells function a sensor. The present study aimed clarify sensor-hypothalamic neural pathway activated response glucoprivation mediate counterregul...

Fenfluramine reduces hunger and promotes body weight loss by increasing central serotonin (5-HT) signaling. More recently, neuropeptides have been linked to the regulation of feeding behavior, metabolism and body weight. To examine possible interactions between 5-HT and neuropeptides in appetite control, fenfluramine (200 nmol/0.5 μl/side) was administered directly into the hypothalamic paraven...

The central representation of neurogenically mediated coronary vasoconstriction produced by activation of the sympathetic nervous system was examined in anesthetized cats instrumented for continuous recording of coronary and femoral blood flows, arterial pressure, and heart rate. Electrical stimulation in a small region of perifornical lateral hypothalamus increased arterial pressure, heart rat...