نتایج جستجو برای: paraoxonase
تعداد نتایج: 2123 فیلتر نتایج به سال:
Background: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease is increasing in adults and children worldwide. Obesity, insulin resistance or diabetes type II, hyperlipidemia and hypertriglyceridemia plays a major role in the epidemiology of this disease. Cytokeratin 18 (CK-18) the major intermediate filament protein in the liver is a marker of increased hepatocyte apoptosis. ...
Introduction: The aim of this research was to investigate the effect of eight weeks of aerobic exercise and Chlorella supplementation on paraoxonase-1 and lipid hydroperoxide in Wistar rats with type 2 diabetes. Methods: The present study is an experimental research. 50 male Wistar rats with an average weight of 220±10 g were divided into 5 groups of normal control, diabetic control, di...
Background: Paraoxonase-1 (PON1) moves with high-density lipoprotein (HDL) particles in blood and prevents low-density lipoprotein (LDL) particles from oxidation. The aims of this study were to investigate the correlation between fatty acid composition of HDL phospholipids with pon-1 polymorphisms and response to lovastatin treatment in people with high blood cholesterol. Methods: In this desc...
background: arsenic as an environmental toxicant is able to induced oxidative stress. the present study aimed to evaluate of vitamin c supplementation on the paraoxonase1 (pon1) arylesterase activity (responsible for hydrolysing lipid-peroxides) in rat exposed to arsenic. methods: the study was conducted in the faculty of veterinary medicine, tabriz islamic azad university, tabriz, iran in 2001...
Abstract Introduction Paraoxonase 1 is an enzyme associated with high-density lipoprotein fraction and considered to present antioxidant activity. Objectives The aim of the study was assess arylesterase activity paraoxonase (PON1) in serum patients hypertension, due effect therapy before treatment. Patients Methods. conducted 76 primary hypertension 28 volunteers for control group. Hypertensive...
The differentiation of paraoxonase (an A-type esterase in serum) from related enzymes has been complicated by overlapping substrate specificities and by the complex nature of these enzymes. Rabbit-serum paraoxonase has been differentiated from hog-kidney diisopropyl phosphorofluoridatase by Mounter (1954). He confirmed the observation of Aldridge (1953b) that one enzyme in rabbit serum hydrolys...
Background: Thymus species have significant amounts of phenolic and flavonoid compounds and demonstrate strong antioxidant activities. Paraoxonase1 act as antioxidant enzyme and protect the low-density lipoprotein against oxidation. In our study we aimed to evaluate the antioxidant capacity of Thymus Kotschyanus Hydroalcoholic extract and its effect on serum paraoxonase 1 activity in healthy an...
BACKGROUND The circulating cholinesterases acetyl- and butyrylcholinesterase may be suppressed and subsequently released from the brain in acute bacterial meningitis. METHODS We report serum activities of acetylcholinesterase and butyrylcholinesterase in paired arterial and jugular venous samples from seven patients with acute bacterial meningitis and eight healthy controls. Paraoxonase 1, wh...
The Focus article "Double Exposure" [EHP 107:A196-A201 (1999)] mistakenly reported that a meta-analysis of epidemiology studies examining the relationship between exposure to environmental tobacco smoke (ETS) and human cancer was prepared for the review of ETS in consideration for listing in the National Toxicology Program (NTP) Report on Carcinogens. We would like to point out that the results...
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