Malignant paraganglioma of the urinary bladder is a rare tumor. Clinical diagnosis of this tumor relies on high index of suspicion and high levels of blood and urine catecholamines. The malignancy of the paraganglioma is established upon the presence of local aggressive behavior or distant metastasis. Imaging studies play an important role in detecting tumor foci, in determining the extent of t...

Med J Malaysia Vol 68 No 4 August 2013 INTRODUCTION A glomus tumor is known as a solid glomus tumor, glomangioma, nonchromaffin paraganglioma and paraganglioma. It typically present as a solitary, small and located in the subungual region. In rare cases, the tumor may present in other body area such as tympanic membrane, gastric antrum or glands penis. We describe a patient presented with a lar...

A 66-year-old man with symptomatic hypertensive episodes was found to have a 9-mm adrenal mass and elevated metanephrine levels. He was scheduled for an adrenalectomy for suspected pheochromocytoma. Subsequent workup revealed a large bladder mass which was found to be a paraganglioma. There is no consensus on what should be considered the standard management of primary bladder paraganglioma, in...

Paragangliomas are neuroendocrine tumours and those occurring in the head and neck have well recognized familial association. Retroperitoneal paragangliomas are uncommon and we present two cases of familial malignant retroperitoneal paraganglioma. Review of the literature revealed marked differences in the incidence and malignant potential of familial and non-familial paraganglioma. In contrast...

Paraganglioma rarely occurs in the spinal canal. Paraganglioma of the cauda equina has been reported in only 25 cases in the world literature since first reported by Lerman, et al., in 1972. In 1970, Miller reviewed the first case of these, but he confused it with secretory ependymoma. The characteristic histologic appearance is of a Zellballen pattern that consists of polygonal cells separated...

UNLABELLED Paragangliomas are rare neoplasms arising from undifferentiated cells of the primitive neural crest. We report a case of a 57-year-old patient with renal pigmented paraganglioma that was an incidental finding. Histopathological examination showed typical morphology of paraganglioma, as well as the unusual feature of large amounts of pigment in the cytoplasm of the tumor cells which w...

Tumor-to-tumor metastasis (TTM) is a relatively rare but well-documented phenomenon. The authors report a unique case of esophageal carcinoma metastatic to an intracranial paraganglioma. A sellar and suprasellar tumor was found using MR imaging in an 81-year-old man who presented with a 3-week history of progressive headache and blurred vision. A subtotal excision of the tumor was achieved. His...

Carney triad is a rare syndrome of unknown etiology characterized by having at least two out of three following neoplasms: gastrointestinal stromal tumor, pulmonary chondroma and extra-adrenal paraganglioma. About 100 cases have been reported worldwide. We report a case of Carney triad in a 42-year-old woman presented with a gastrointestinal stromal tumor in the stomach and a malignant function...

Received June 2007 Accepted September 2007 INTRODUCTION Paraganglioma of the urinary bladder is rarely encountered and its biological behavior is uncertain. It represents less than 1% of the bladder tumors and is usually benign. The tumor usually develops in young adult women.(1) The most prevalent involved sites are discussed controversially in the literature. In a recently published work, lat...

BACKGROUND Pigmented paraganglioma is a special type of paraganglioma, and it is rare in the thyroid. CASE PRESENTATION We report a case of a 41-year-old woman who had complained of a mass in the thyroid gland. Histology revealed tumor cells arranged in a nest-like or organoid pattern, separated by delicate fibrovascular septa. Two distinct components were observed. In the first, which consti...