OBJECTIVE To describe quantitative cytophotometric expression of the marker caspase-3 in colloid goiter and in papillary carcinoma of the thyroid, comparing the immunoexpression between them. METHODS An immunohistochemistry study has been made on the protein caspase-3 in 17 of paraffin blocks of papillary carcinoma of the thyroid and 20 cases of colloid goiter, using SAMBA 4000 ® (System of M...

Our experience with 12 papillary breast lesions included eight intraductal papillomas, three primary papillary carcinomas, and one metastatic papillary ovarian carcinoma. Five of the eight intraductal papillomas displayed diagnostic findings including tridimensional papillary fragments of ductal cells with distended cytoplasmic vacoules and dense scalloped cytoplasm. Three intraductal papilloma...

thyroid cancer is the most common endocrine malignancy. this study surveys the pathologic characteristics of thyroid cancerin mashhad and study of papillary carcinoma in more detail. in this retrospective study, 108 out of 197 cases of thyroid cancer were papillary in type (55%), with female to male ratio of 1.91 which is lower than current reports. the age at the time of diagnosis ranged from ...

♦Corresponding Author: Negar Azarpira, MD Organ Transplant Research Center, Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran Tel: +98-711-647 4331 Email: [email protected] Introduction The presence of synchronous malignant tumors in patients with squamous cell carcinoma (SCC) of the pharynx is not a rare event. This is important because it can decrease the overall su...

Introduction: While it can be difficult to categorize thyroid lesions, employing ultrasound may enable correct diagnosis, classification, and therapy of nodules, particularly papillary carcinoma the thyroid, assist save unneeded biopsy. Objective: Taking histopathology as gold standard, assessing diagnostic precision in identification cancer nodule patients. Study design: Cross sectional study ...

OBJECTIVE Papillary thyroid carcinoma (PTC) is the most frequent types of thyroid malignancies. Several genes may be involved in susceptibility of thyroid cancer including Human Leukocyte Antigens (HLA). The association of thyroid carcinoma with HLA alleles has been previously studied in other populations and certain HLA alleles were shown to be either predisposing or protective. The aim of thi...

OBJECTIVE We wanted to assess the need for surgical excising papillary lesions of the breast that were diagnosed upon sonographically guided 14-gauge core needle biopsy. MATERIALS AND METHODS Sixty-nine women (age range: 25-74 years, mean age: 51.7 years) with 69 papillary lesions (4.9%) were diagnosed and followed after performing sonographically guided 14-gauge core needle biopsies. Surgica...

INTRODUCTION Papillary carcinoma is the most common malignant thyroid neoplasm. The effect of the concurrent presence of Hashimoto's thyroiditis and papillary thyroid carcinoma remains controversial. OBJECTIVE To evaluate the association between Hashimoto's thyroiditis and clinicopathological parameters in thyroid papillary carcinoma cases, based on an historical institutional cohort analysis...

OBJECTIVE To clarify the diagnostic significance of nuclear grooves in thyroid fine needle aspirates, to search for other associated nuclear features and to identify possible diagnostic pitfalls. STUDY DESIGN In total, 67 fine needle aspiration cases were retrospectively reviewed for selected nuclear features, including grooves, intranuclear cytoplasmic invaginations, enlargement, pleomorphis...

PURPOSE To investigate clinical characteristics and surgical treatment of multifocal papillary thyroid carcinoma. METHODS A total of 648 patients diagnosed with papillary thyroid carcinoma were enrolled, 168 with multifocal papillary thyroid carcinoma. Clinicopathological factors including gender, age at diagnosis, family history of thyroid tumor, multiplicity and bilaterality of tumor, extra...