OBJECT The purpose of the current study was to investigate alterations of regional cerebral blood flow (rCBF) in subjects with panic disorder. METHODS Twenty-two subjects with panic disorder who were under psychotropic medications and 25 age and gender-matched healthy comparison subjects were assessed regarding the rCBF of using Tc-99m-hexamethyl propylenamino oxime single photon emission tom...

Object: The purpose of the current study was to investigate alterations of regional cerebral blood flow (rCBF) in subjects with panic disorder. Methods: Twenty-two subjects with panic disorder who were under psychotropic medications and 25 age and gender-matched healthy comparison subjects were assessed regarding the rCBF of using Tc-99m-hexamethyl propylenamino oxime single photon emission tom...

Panic disorder is characterized by a progression of panic symptom severity with repeated attacks. Repeated panic episodes evoke heightened anticipatory anxiety, phobic avoidance and are typically associated with comorbid symptoms of depression. Due to the heterogeneity of the disorder, reliable neurochemical correlates attending panic have not been identified. However, variable neuropeptide int...

The current diagnostic criteria for panic disorder, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV, American Psychiatric Association, 1994), are comprised of recurrent unexpected panic attacks, and anxiety about future panic attacks or their consequences, or a significant behavioral change because of the panic attacks. The additional anxiety about pa...

OBJECTIVE Classical conditioning features prominently in many etiological accounts of panic disorder. According to such accounts, neutral conditioned stimuli present during panic attacks acquire panicogenic properties. Conditioned stimuli triggering panic symptoms are not limited to the original conditioned stimuli but are thought to generalize to stimuli resembling those co-occurring with pani...

OBJECTIVE To identify the association between panic disorder and licit and illicit substance use in the population provided with primary care in the southern Brazil. METHODS This is a cross-sectional study with patients from three primary care centers. We used the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) to evaluate substance use and the Mini International Neuropsych...

Aim: To study the prevalence of psychiatric diagnosis and psychopathology in adolescent offspring of parents with panic disorder, depression and normal controls Methods: Adolescent offspring (11-16 years) of parents with a diagnosis of panic disorder and major depression, and normal controls were interviewed using Missouri Assessment of Genetics Interview for Children (MAGIC), Scale for Childho...

BACKGROUND Many people suffer from subthreshold and mild panic disorder and are at risk of developing more severe panic disorder. AIMS This study (trial registration: ISRCTN33407455) was conducted to evaluate the effectiveness of an early group intervention based on cognitive-behavioural principles to reduce panic disorder symptomatology. METHOD Participants with subthreshold or mild panic ...

The present study examined the frequency and characteristics of panic disorder in children and adolescents who had been referred to a pediatric psychopharmacology clinic. Of the 280 children and adolescents evaluated in this clinic, 35 were diagnosed with panic disorder using a semi-structured clinical interview (K-SADS) and other objective measures. Approximately half of the youngsters with pa...

PURPOSE Epidemiological studies have identified a trend in the development of depressive and anxiety disorders following a diagnosis of sleep apnea. The relationship between sleep apnea and subsequent panic disorder, however, remains unclear. METHODS Using a nationwide database, the Taiwan National Health Insurance Research Database, patients with sleep apnea and age-, sex-, income-, and urba...