Pancreas divisum-failure of fusion of the dorsal and ventral pancreatic ducts-is relatively well known as the most common congenital anomaly of the pancreatic duct, of with an incidence approximately 10% of all embryos. And there is a rare anomaly similar to pancreas divisum in which doubled ducts are formed. This condition is a rare developmental anomaly called pancreas bifidum or bifid pancre...

Over the last 15 years whole organ pancreas transplantation has emerged as the treatment of choice for selected patients with uremia and Type I Diabetes Mellitus. Improvements in surgical technique, better understanding of transplant related complications and advances in immunosuppressive therapy have encouraged the application of this procedure to an increasing number of patients. Pancreas tra...

Understanding how the pancreas develops is essential to understand the pathogenesis of congenital pancreatic anomalies. Recent studies have shown the advantages of investigating the development of frogs, mice, and chickens for understanding early embryonic development of the pancreas and congenital anomalies, such as choledochal cysts, anomalous pancreaticobiliary junction, annular pancreas, an...

Abstract Purpose of Review ? cell replacement via whole pancreas or islet transplantation has greatly evolved for the cure type 1 diabetes. Both these strategies are however still affected by several limitations. Pancreas bioengineering holds potential to overcome hurdles aiming repair and regenerate compartment. In this review, we detail state-of-the-art recent progress in field applied diabet...

Abstract Papillary thyroid cancer (PTC) is the most common endocrine malignancy, accounting for 85% of differentiated cancers. A small percentage PTC variants are considered more aggressive, such as tall cell variant associated with V600E mutation in BRAF gene and rarer columnar variant, which described only 0.2% cases has a poor prognosis. Although locoregional metastases to neck lymph nodes c...

Congenital duodenal stenosis is one of the most common causes of neonatal obstruction, which is frequently associated with annular pancreas and Down syndrome. Ectopic pancreas is defined as an abnormally situated pancreatic mass that lacks contact with normal pancreas. Although the association between duodenal stenosis and annular pancreas is very common, the presence of an ectopic island of pa...

The annular pancreas is a rare congenital anomaly in which a ring of the pancreas parenchyma surrounds the second part of the duodenum. Malignant tumors are extremely rare in patients with an annular pancreas. A 64-year-old man presented with appetite loss and vomiting. Abdominal contrast-enhanced computed tomography (CT) indicated pancreas parenchyma surrounding the second part of the duodenum...