Panax ginseng occupies an important place among the tonic remedies of Oriental medicine. Pharmacological investigations show that crude ginsenosides can increase non-specific resistance of an organism to various untoward influences. The effects of purified derived derivatives have only recently become better studied in immunological and cell growth studies in animals and in man. This has now pr...

Panax ginseng has been used as a medicinal plant in China for thousands of years. Current use in Western countries has been diverse, with focused research on cancer therapeutics. P. ginseng apparently mitigates cancer through anti-inflammatory, antioxidant, and apoptotic mechanisms to influence gene expression. Additional mechanisms of investigation include influence on neurotransmission and im...

A liquid chromatographic method was developed and validated for the determination of ginsenosides in Panax ginseng roots by using evaporative light-scattering detection. Eighteen ginsenosides were separated on a reversed-phase C18 column with water-ammonium acetate-acetonitrile as the mobile phase. The method is suitable for the routine determination of ginsenosides in P. ginseng roots and extr...

BACKGROUND Korean ginseng (Panax ginseng) is one of the most important medicinal plants in the Orient. Among nine cultivars of P. ginseng, Chunpoong commands a much greater market value and has been planted widely in Korea. Chunpoong has superior quality "Chunsam" (1st grade ginseng) when made into red ginseng. METHODS A rapid and reliable method for discriminating the Chunpoong cultivar was ...

The acute effect of Panax ginseng (GS), root extract was investigated on the rate of glycogenolysis in white muscle and in liver during prolonged exercise of 3 hours duration in rats. Adrenal cholesterol depletion was also measured. GS inhibited decrease of adrenal cholesterol by 21% after 3 hours of swimming. GS had no effect on hepatic glycogen, but had pronounced inhibitory effects on endoge...

BACKGROUND Panax ginseng has been used as Korean medicine for various diseases. It has antioxidant, hypotensive, sedative, analgesic, and endocrine activities. Dammarane-type triterpenes from the plant have various beneficial effects. METHODS A dammarane-type triterpene saponin was isolated from P. ginseng root through chromatography such as repeated column chromatography and medium pressure ...

Panax ginseng occupies an important place among the tonic remedies of Oriental medicine. Pharmacological investigations show that crude ginsenosides can increase non-specific resistance of an organism to various untoward influences. The effects of purified derived derivatives have only recently become better studied in immunological and cell growth studies in animals and in man. This has now pr...

PREMISE OF THE STUDY Highly transferable expressed sequence tag (EST) microsatellites were developed for Panax ginseng (Araliaceae), one of the most celebrated traditional Chinese medicines and an endangered species in East Asia, using whole-genome data. METHODS AND RESULTS Twenty-one EST microsatellites were characterized from next-generation sequencing and were composed of di- and trinucleo...

Purpose: To investigate the mode of action active ingredients Panax ginseng against ovarian cancer protein targets elucidated using a network pharmacology approach and molecular docking study. Methods: An integrated protein-protein interactions (PPI) targeting P. was constructed carried out for constituents target ginseng. Results: Ninety-six compounds were used simulation five different protei...