As neurons age, their survival depends on eliminating a growing burden of damaged, potentially toxic proteins and organelles-a capability that declines owing to aging and disease factors. Here, we review the two proteolytic systems principally responsible for protein quality control in neurons and their important contributions to Alzheimer disease pathogenesis. In the first section, the discove...

Using the concept of intersectionality, this rhetorical analysis combines feminist and critical cultural theories to explore the meanings of the ―independent woman‖ in the lyrics and respective videos of male and female rappers. Findings indicate both groups use misogynistic language to describe women and juxtapose images of independence with material wealth. However, male rappers are more like...

THE RELATIONSHIP BETWEEN READING ABILITY AND SYNTACTICAL MEDIATION IN PAIRED-ASSOCIATE (PA) LEARNING WAS EXAMINED. SUBJECTS WERE 64 FOURTH AND SECOND GRADERS IN WISCONSIN WHO WERE GROUPED ACCORDING TO GRADE LEVEL, TWO READING LEVELS, TWO TYPES OF INSTRUCTION, AND SEX. THE INSTRUCTIONAL TYPES WERE MEDIATION AND NONMEDIATION: THE STIMULI WERE 16 PICTURES PAIRED TO MINIMIZE ASSOCIATION VALUE. THE ...

The steps that commit multipotential somite cells to muscle differentiation are being elucidated. Recent results show that pax3 is an upstream regulator of myoD, one of the key genes in myogenic lineage determination.

T he occurrence of a premature beat between two consecutive conducted sinus beats is termed an interpolated premature systole or extrasystole.1 An interpolated premature ventricular systole can effect the conduction of the subsequent sinus beat by concealed retrograde penetration into the His-Purkinje system or AV node or both. This retrograde concealed penetration can result in a prolongation ...

Six genera and 27 species of hard ticks (Ixodidae) currently are recognized in the United States east of the Mississippi River as follows: Amblyomma (4 species), Boophilus (1), Dermacentor (3), Haemaphysalis (2), Ixodes (16), and Rhipicephalus (1). We present a diagrammatic couplet key to the adults of the six genera and 27 species of Ixodidae found in the eastern portion of the United States.

This paper investigates the steady hydromagnetic three-dimensional boundary layer flow of Maxwell fluid over a bidirectional stretching surface. Both cases of prescribed surface temperature (PST) and prescribed surface heat flux (PHF) are considered. Computations are made for the velocities and temperatures. Results are plotted and analyzed for PST and PHF cases. Convergence analysis is present...

Nathaniel N. Ivers, NCC, is an Assistant Professor and Associate Chair of the Department of Counseling at Wake Forest University. José A. Villalba is a Professor and Associate Dean at Wake Forest University. Correspondence may be addressed to Nathaniel N. Ivers, Wake Forest University, Department of Counseling, P.O. Box 7406, Winston-Salem, NC 27109, [email protected]. Nathaniel N. Ivers, José A....