Seed–storage proteins are important reservoirs of food and energy which are also involved in the determination of bread making quality. Solubility properties of these proteins are traditionally classified into four classes: albumin, globulin, prolamin and glutelin. Gliadin and glutenin have also been studied extensively and the genetics and biochemistry are relatively well known. Grain proteins...

In genetically predisposed individuals, ingestion of wheat gliadin provokes a T-cell-mediated enteropathy, celiac disease. Gliadin fragments were previously reported to induce phenotypic maturation and Th1 cytokine production by human dendritic cells (DCs) and to boost their capacity to stimulate allogeneic T cells. Here, we monitor the effects of gliadin on migratory capacities of DCs. Using t...

helicobacter pylori infections are accompanied with the release of some antigenic material into the stool. outer membranes proteins (omp) are among the major antigens of bacteria, which in comparison with other bacterial constituents have less cross-reactivity. in this study, omp of h. pylori were isolated from 11 clinical isolates and rabbit antiserum against them was used to detect possible a...

celiac disease is the inability of the small intestine to tolerate some cereal prolamin with sequence specific oligopeptide. wheat gliadin, rye secalins and barley hordenine are the main proteins involved in the disease mechanisms and may provoke an inflammatory process to damage the small intestine. there are different methods to overcome the problems for such patients one of them is using glu...

conclusions the results of the present study showed that the baculovirus expression system (sf9 cells) was able to express truncated orf2 and truncated orf2-nsp4 proteins as a potential candidate vaccine. background the hepatitis e virus (hev) accounts for hepatitis e infection with relatively high mortality rate in pregnant women that can lead to fulminant hepatitis. the baculovirus expression...

PURPOSE Celiac disease (CD) is an autoimmune enteropathy, triggered by dietary gluten. The only treatment is a strict gluten-free diet. Oats are included in the list of gluten-free ingredients by European Regulation, but the safety of oats in CD is still a matter of debate. The present study examined the capability of different oat cultivars of activating the gliadin-induced transglutaminase-2 ...

ALTHOUGH the action of aqueous solutions of aldehydes upon proteins has been extensively studied, the behaviour of aldehydes in the anhydrous state does not seem to have been investigated in detail, except for the single observation of Mathewson [1906] that gliadin appeared to be somewhat soluble in impure benzaldehyde. Apart from its chemical interest such an investigation might lead to improv...

Gluten proteins are major determinants of the bread making quality of wheat but also of important gluten-related disorders. The gluten protein accumulation during grain filling is strongly influenced by nitrogen fertilization. We have characterized the gluten proteins in low-gliadin wheat lines as influenced by nitrogen treatments in two experiments. These transgenic lines, D783, D793, C655, D5...