In this study, the diuretic activity of powdered cherry stalk was evaluated in 13 healthy volunteers by means of their water balance. In addition to biochemical parameters, such as urinary electrolyte concentration, osmolality and any adverse reaction were determined. The capsules of cherry stalks were administered at an equivalent dose of 2.0 grams of the plant per person. Urinary biochemical ...

Five human immunodeficiency virus-infected patients with disseminated Mycobacterium avium complex infection had progressive weight loss and persistent fever despite multidrug antimycobacterial therapy. These patients were given daily low-dose oral dexamethasone (typically 2 mg/day) as adjunctive therapy. All had substantial and sustained weight gain (12 to 50% of pre-steroid treatment body weig...

UV light inactivation of Mycobacterium avium subsp. paratuberculosis in Middlebrook 7H9 broth and whole and semiskim milk was investigated using a laboratory-scale UV machine that incorporated static mixers within UV-penetrable pipes. UV treatment proved to be less effective in killing M. avium subsp. paratuberculosis suspended in milk (0.5- to 1.0-log(10) reduction per 1,000 mJ/ml) than that s...

Background Therapeutic management of Mycobacterium avium infection is inadequate due to patient non-compliance, lengthy treatment regimen, multidrug associated toxic side-effects etc. particularly in AIDS patients who are at a greater risk of developing mycobacterial infection. This study was designed to evaluate chemotherapeutic potential of poly D, L-lactide-co-glycolide nanoparticles against...

Jensen, D., Lieu, T., Halls, M., Veldhuis, N., Imlach, W., Mai, Q., Poole, D., Quach, T., Aurelio, L., Conner, J., Robinson, P., Christie, M., et al (2017). Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief. Science Translational Medicine, 9(392), 1-15. <a href="http://dx.doi.org/10.1126/scitranslmed.aal3447"...

Let $G$ be a bipartite graph. In this paper we consider the two kind of location problems namely $p$-center and $p$-median problems on bipartite graphs. The $p$-center and $p$-median problems asks to find a subset of vertices of cardinality $p$, so that respectively the maximum and sum of the distances from this set to all other vertices in $G$ is minimized. For each case we present some proper...

Microorganisms are important components of soil. Some soil filamentous fungi such asPenicilium produce many bioactive small molecules, or secondary metabolites, that range frombeneficial bioactive compounds to harmful toxins. In this study, the metabolites of threepenicillium species (P. goditanum, P. moldavicum and P. corylophilum) were extracted byadding ethyl acetate to liquid cultures. The ...

The efficiency of four culture media was compared for the isolation of Mycobacterium avium complex from 197 procine tissues. In 82 tissues with microscopic granulomas and acid-fast bacilli, a significantly greater number of isolates were obtained on Middlebrook 7H10 medium with sodium pyruvate than on Stonebrink medium, Herrold egg yolk agar medium, or Lowenstein-Jensen medium (P=0.01). In 46 t...