Intraoperative oxygen supplementation to sedated children has been shown to prevent hemoglobin desaturations even in the presence of apnea during pediatric conscious sedation. Although many practitioners deliver supplemental oxygen via a nasal hood, this method is impractical and often unsuccessful if the child is a mouth breather, has moderate adenotonsillar hypertrophy or occasionally cries d...

iron is essential to erythrocyte oxygen transport and is a catalyst for oxidative metabolism in all cells. iron is absorbed by the duodenum and requires an acidic environment for optimal absorption. iron is found for 70% in erythrocytes, and 30% in storage, and a small amount in myoglobin and cytochromes. iron supplementation reduces anemia in breastfed infants and increases in significant dose...

The effect of regular intake of low doses of an effervescent multivitamin preparation on the free-radical-producing activity of murine peritoneal macrophages under conditions resembling a possible infection was studied in vitro. Initially, several groups of mice were fed a basal diet and given, for 2 weeks, water without or with supplementation of either alpha -tocopherol, ascorbic acid, ribofl...

PURPOSE Echinacea is an herbal supplement used by endurance athletes for its performance boosting properties. It is thought that Echinacea improves the blood's oxygen carrying capacity by increasing production of erythropoietin (EPO), a glycoprotein that regulates red blood cell formation. Subsequently, these changes would lead to an overall improvement in maximal oxygen uptake (VO2max) and run...

Abstract The effects of wheat gluten hydrolysates (WGH) and their ethanol elution fractions obtained on XAD-16 resin physiological activity fermentation performance brewer’s yeast during very-high-gravity (VHG) worts were investigated. results showed that the addition WGH in VHG significantly enhanced biomass viability, further increased fermentability, yield productivity yeast. Supplementation...

Conventional chemotherapy targets proliferating cancer cells, but most cells in solid tumors are not in a proliferative state. Thus, strategies to enable conventional chemotherapy to target noncycling cells may greatly increase tumor responsiveness. In this study, we used a 3-dimensional tissue culture system to assay diffusible factors that can limit proliferation in the context of the tumor m...

Conventional chemotherapy targets proliferating cancer cells, but most cells in solid tumors are not in a proliferative state. Thus, strategies to enable conventional chemotherapy to target noncycling cells may greatly increase tumor responsiveness. In this study, we used a 3-dimensional tissue culture system to assay diffusible factors that can limit proliferation in the context of the tumor m...

The thyroid is the organ with the highest selenium content per gram of tissue because it expresses specific selenoproteins. Since the discovery of myxoedematous cretinism and thyroid destruction following selenium repletion in iodine- and selenium-deficient children, data on links between thyroid metabolism and selenium have multiplied. Although very minor amounts of selenium appear sufficient ...

INTRODUCTION cell-based tissue engineering strategies using human mesenchymal stem cells (hMSCs) may help to augment tendon healing. To further investigate the in-vitro behavior of this cell population, we investigated low oxygen culture levels, and growth factor supplementation and their effect on expression of tendon extracellular proteins and cell proliferation. MATERIALS AND METHODS bone ...

Oxygen therapy, a lifeline for many critically ill patients, can be delivered in nonintubated patients via several devices. unlike patients with chronic hypoxemia, the long-term comfort and cosmetics of the patient are not a concern of intensivists; instead, the goal is to ensure adequate oxygen delivery to prevent hypoxemia. although hypoxemia is often corrected with oxygen therapy, care shoul...