this study was conducted to evaluate the cytoprotection of various extracts and bioactive compounds found in pistacia vera againts cytotoxicity, ros formation, lipid peroxidation, protein carbonylation , mitochondrial and lysosomal membrane damages in cell toxicity models of diabetes related carbonyl (glyoxal) and oxidative stress (hydroperoxide). methanol, water and ethyl acetate were used to ...

conclusions despite the presence of vast oxidative stress in hepatitis b, antioxidant therapy is not always effective as a treatment strategy, especially considering that antioxidants can act as “double-edged swords” or antioxidants; if not used at the right time or place or in the right combination, these substances can easily become pro-oxidants. therefore, several studies will be needed to d...

abstract background and objective: it has been shown that oxidative stress increases in diabetes and it has an important role in its development and subsequent complications. thus, the aim of this study was to investigate the effect of acute resistance exercise on oxidative stress in skeletal muscle and cardiac tissues of streptozotocin-induced diabetic rats. materials and methods: twenty male ...

conclusions lead contamination in the presence of an emf exacerbates the oxidative damage to plasma proteins as well as the conformational changes in hb. an artificial neural network can be used as a predictive tool for the oxidative danger posed to workers in industrial fields, battery manufacturing companies, and power plants. patients and methods in this experimental study, the blood samples...

objective(s): nanotechnology and nanoparticles are increasingly recognized for their potential applications in aerospace engineering, nanoelectronics, and environmental remediation, medicine and consumer products. more importantly is the potential for the application of silver nanoparticles (ag nps) in the treatment of diseases that require maintenance of circulating drug concentration or targe...

objectives: curcumin has anti-inflammatory and antioxidative properties. the objective of this study was to investigate the therapeutic effects of curcumin on functional disturbances, oxidative stress, and leukocyte infiltration induced by renal ischemia/reperfusion (i/r). materials and methods: animals were randomly divided into 9 groups. the groups with 24-h reperfusion consisted of sham-24h,...

introduction: this study was designed to evaluate the effects of treatment with flaxseed oil (fso) on renal ischemia-reperfusion (rir) injuries in rats. materials and methods: in this study, 32 wistar rats were randomly studied in four groups: co+ns (control group with normal saline administration), sh+ns (sham group with normal saline administration), rir+ns and rir+fso. fso (0.2 ml) was admin...

background: recent results have provided increasing evidence to support involvement of membrane damage in the mechanism of ionizing radiation induced killing of mammalian cells. these findings have stimulated renewed interest in evaluating the damage to membrane as a primary initiator in radiation-induced cell killing especially in apoptotic death. the present study was aimed to gain deeper ins...

background: glucocorticoids have several benefits in large animal medicine but apart from their benefits, there are several disadvantages attributed to the use of these drugs. among the disadvantages, disturbance in protein metabolism is one of the side effects of glucocorticoids which has been investigated in human and laboratory animals. objectives: there are no information regarding the effe...

toxic effects of monensin, a polyether antibiotic mainly used as a coccidiostat, have been described in a wide range of animals. the present study was performed to investigate the toxic effects of monensin in goats. seven adult goats were administered sodium monensin, 13.5 mg kg-1, daily for five consecutive days via gastric gavage. monensin toxicity was evaluated by clinical signs, serum bioch...