The exact mechanisms underlying the role of oxidative stress in the pathogenesis and the prothrombotic or proinflammatory status of antiphospholipid syndrome (APS) remain unknown. Here, we investigate the role of oxidative stress and mitochondrial dysfunction in the proatherothrombotic status of APS patients induced by IgG-antiphospholipid antibodies and the beneficial effects of supplementing ...

OBJECTIVE Oxidative stress has been shown to contribute to the pathogenesis of acute and chronic lung inflammatory diseases. This article aimed to evaluate the oxidant/antioxidant status of children with acute bronchiolitis through the measurement of plasma total antioxidant capacity, total oxidant status, and oxidative stress index. METHODS Children with acute bronchiolitis admitted to the p...

BACKGROUND Red wine contains a naturally rich source of antioxidants, which may protect the body from oxidative stress, a determinant of age-related disease. The current study set out to determine the in vivo effects of moderate red wine consumption on antioxidant status and oxidative stress in the circulation. METHODS 20 young (18-30 yrs) and 20 older (>or= 50 yrs) volunteers were recruited....

OBJECTIVE The aim of this study was to elucidate the etiology and treatment of primary ovarian insufficiency, which is of unknown cause in 95% of the cases. MATERIALS AND METHODS Thirty patients aged 18-40 years who presented to Dicle University Faculty of Medicine Clinic of Obstetrics and Gynecology between June 2012 and January 2014 and were diagnosed as having primary ovarian insufficiency...

OBJECTIVES The purpose of this study was to determine the impact of changes in oxidative stress and antioxidant status in response to playing tennis in HOT (∼36°C and 35% relative humidity (RH)) and COOL (∼22°C and 70% RH) conditions. METHODS 10 male tennis players undertook two matches for an effective playing time (ie, ball in play) of 20 min, corresponding to ∼122 and ∼107 min of total pla...

BACKGROUND F. hepatica infection is rare and mostly subclinical. Migration of juvenile forms of F. hepatica into the host's liver is accompanied by an inflammatory reaction followed by fibrosis and cirrhosis. OBJECTIVE The aim of this study was to evaluate oxidative status by using a novel automated method in patients with Fasciola hepatica. METHODS Twenty two patients with a diagnosis of F...

OBJECTIVE Etiology of premature preterm rupture of membranes (PPROM) is not yet completely known and chorioamnionitis is one of the most important complications of its. We aimed to evaluate whether prolidase, matrix metalloproteinases, oxidative-antioxidative status, and inflammation markers in vaginal washing fluid (VWF) were associated with etiology of PPROM and whether these markers could be...

1. The ‘parasite-mediated sexual selection’ (PMSS) hypothesis predicts that exaggerated male ornamentation could provide a signal to females of a male’s ability to resist parasites. Empirical tests of the PMSS have been largely equivocal, however, which may be because most have not considered the role of early life-history effects. 2. Many sexually selected traits are carotenoid-based. Allocati...

There is a controversy over the effects of testosterone supplements on dopaminergic function. Both neuroprotective and toxic effects of testosterone supplements are reported. The status of oxidative stress seems to explain the neuroprotective or toxic properties of testosterone. To determine the efficacy of testosterone supplements in different status of oxidative stress, the present studies an...

The aim of the present study is to evaluate the relationship of total antioxidant capacity, total oxidant status, oxidative stres and total free sulfydryl groups in patients with diabetic and nondiabetic senil cataract. The study was carried out on venous blood samples from 70 subjects admitted to the ophtalmology clinic of a research hospital. Of these, 25 were senile Type 2 diabetic patients ...