Sclerosing stromal tumor of the ovary is a rare, benign ovarian tumor, seen primarily in young women. We report a 3-year-old girl who presented with a palpable lower abdominal mass. Computed Tomography (CT) study revealed a huge pelvic mass with an enhancement pattern typical of ovarian sclerosing stromal tumor. The diagnosis was confirmed by pathology examination of the surgically resected tum...

The first tissue-specific angiogenic molecule, endocrine gland-derived vascular endothelial growth factor (EG-VEGF), was identified recently in human ovary, raising hopes of developing tumor type-specific angiogenesis inhibitors. In the present study, we analyzed the expression of EG-VEGF mRNA in normal human tissues and ovarian neoplasms by quantitative real-time reverse transcription-PCR. EG-...

BACKGROUND Mucinous cystic neoplasms arise in the ovary and various extra-ovarian sites. While their pathogenesis remains conjectural, their similarities suggest a common pathway of development. There have been rare reports involving the mesentery as a primary tumour site. CASE PRESENTATION A cystic mass of uncertain origin was demonstrated radiologically in a 22 year old female with chronic ...

Ovarian neoplasms are group of aggressive and lethal diseases. Surgical and radiochemical therapies on ovarian neoplasm are conventional approaches but with limited progress in years. Targeted therapy with drugs targeting specific genetic alterations and/or protein molecules have brought new hope fighting against ovarian neoplasms. Targeted therapy on genetic alterations of BRAF, ROS-1 and HER2...

Stathmin 1 (STMN1) is a biomarker in several types of neoplasms. It plays an important role in cell cycle progression, mitosis, signal transduction and cell migration. In ovaries, STMN1 is predominantly expressed in granulosa cells (GCs). However, little is known about the role of STMN1 in ovary. In this study, we demonstrated that STMN1 is overexpressed in GCs in patients with polycystic ovary...

Throughout the animal kingdom the solid ovarian tumors seem to be infrequent, as they also are, relatively, among human tumors. Cystic tumors are described occasionally, but apparently less frequently in the lower animals than in man. Even among dogs, with their high incidence of tumor growth, ovarian tumors are rare according to the evidence furnished by literature dealing with canine neoplasm...

Spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. Spindle cell neoplasms can affect the oral cavity. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components. This article aims to review the spindle cell neoplasms of the oral cavity with emphasis on histopathology. ...

For the purposes of this paper the term ' radiotherapy ' will be used to cover the established methods of treatment by radium and X-rays. Recent advances in nuclear physics and apparatus construction may materially alter radiotherapy as we know it today by placing in the hands of radiotherapists artificial radioactive substances and machines capable of delivering beams of neutrons, electrons an...

Available statistics on smoking, alcohol, food supply, reproductive history, and other lifestyle habits from the U. S. and Italy were compared and related to mortality rates of common neoplasms over the period 1955 to 1980. Per capita cigarette consumption has declined in the U. S. since the early 1960s but continues to rise in Italy, chiefly due to the recent increase in cigarette smoking amon...

OBJECTIVE To find out the spectrum of various histopathological types of primary neoplasms of different parts/organs of the female reproductive system seen at the Kathmandu University Teaching Hospital (KUTH) as there exists a worldwide wide variation in the distribution of various neoplasms, which appears largely due to exogenous factors rather than due to inherent differences between populati...