Background SMARCA4 is gene whose protein product participates in chromatin remodeling. Somatic mutations in this gene are associated with non-small cell lung cancer and malignant rhabdoid tumors, and both germline and somatic mutations are seen with small cell carcinoma of the ovary, hypercalcemic type. To date, there are no data identifying an association with more common epithelial carcinomas...

Databases pertaining to various diseases provide valuable resources on particular genes of interest but lack the molecular subtype and epithelial-mesenchymal transition status. CSIOVDB is a transcriptomic microarray database of 3,431 human ovarian cancers, including carcinoma of the ovary, fallopian tube, and peritoneum, and metastasis to the ovary. The database also comprises stroma and ovaria...

137 K .M. was a 69-year-old woman who presented to her primary physician with bloating, abdominal cramping, and constipation over the previous weeks. She also noted some fullness in her right groin. She underwent an abdominal ultrasound, which revealed an adnexal mass on the right side of her abdomen, and a computed tomography (CT) scan, which demonstrated a large complex mass in the region of ...

INTRODUCTION Cancer ovary is the third most common malignancy diagnosed in women in Karachi, a moderate to high risk region for the disease. MATERIALS AND METHODS Three hundred and thirty seven cases of ovarian cancer registered at the Karachi Cancer Registry for the years 1995-2002 were reviewed. RESULTS The age- standardized incidence rate (ASR) world per 100,000, crude incidence rate per...

Ovarian cancer is the fifth leading cause of deaths due to cancer among women in the United States. In 2017, 22,440 women are expected to be diagnosed with ovarian cancer and 14,080 women will die with it. Currently used chemotherapies (Cisplatin or platinum/taxane combination) targets cancer cells, but spares cancer stem cells (CSCs), which are responsible for tumor relapse leading to recurren...

This review aims to sketch current scenario of cancers in female reproductive system such as cancer in uterus, ovary, cervix, vagina, vulvar, fallopian tube along with hydatidiform and their treatment strategies.

Patients with myotonic dystrophy are at particularly high risk for cancer arising in the endometrium, brain, colon, or ovary. Giant leiomyoma can occur in patients with myotonic muscular dystrophy, a disease accompanied by muscle wasting.

CCNE1 is one of the most frequent gene amplifications in high grade serous ovarian cancers (HGSOCs), which occurs in at least 20% of HGSOC and in 30% of established ovarian cancer cell lines. Studies with both primary and metastatic ovary tumor specimens further suggest that the abundance of CCNE1 protein expression correlates with tumor progression and predicts a poor prognosis in ovarian canc...

Neuroendocrine carcinomas (NECs) are rare malignancies that originate from the hormone-producing cells of the body's neuroendocrine system. Rectal high grade NEC (HG-NEC) constituting less than 1% of colorectal cancers can cause large ovarian metastasis that may be the initial presenting complaint. Ovarian Krukenberg tumor from a primary rectal HG-NEC is a very unusual and exceedingly uncommon ...

Background: According to some studies in the western countries, %12.7 of total female cancers and %9.8 of all deaths resulted from cancers in the females are due to genital system carcinoma. Methods: The present analytic cross sectional study was done on the cancer registry data of Yazd province for the evaluation of trend of genital carcinoma occurrence amongst females from 2006 to 2010. The t...