OBJECTIVE To test the hypothesis that during the luteal phase of the ovarian cycle, as compared with the follicular phase, the peripheral immune response is shifted toward a type-2 response. DESIGN Prospective study. SETTING Academic research setting. PATIENT(S) Women with regular menstrual cycles. INTERVENTION(S) Blood samples were collected between days 6 and 9 of the menstrual cycle ...

There has been much debate about the role of luteinizing hormone (LH) during follicle stimulating hormone (FSH)-treated ovarian stimulation for assisted reproduction, where the endogenous LH is suppressed using a gonadotrophin-releasing hormone analogue. The requirement for LH in oestradiol biosynthesis is established, but other effects of 'insufficiency' are less clear, and little attention ha...

BACKGROUND This research investigated the response of vascular active factors, vascular endothelial growth factor (VEGF) and angiotensin-II (AT-II) to ovarian stimulation during 24 hours in patients with polycystic ovary syndrome (PCOS). MATERIALS AND METHODS In this clinical trial study, 52 patients with PCOS and 8 control cases were stimulated with human chorionic gonadotropin (HCG) on the ...

Ovarian stimulation is applied in the clinic to restore mono-ovulatory cycles in anovulatory women (ovulation induction) or to induce the development of multiple dominant follicles for assisted reproduction. Ovarian response is the endocrine and follicular reaction of the ovaries to stimulation. Achieving an appropriate ovarian response to anti-estrogens or exogenous gonadotrophins is central t...

BACKGROUND GnRH agonist administration in the luteal phase has been suggested to beneficially affect the outcome of intracytoplasmic sperm injection (ICSI) and embryo transfer (ET) cycles. This blind randomized controlled study evaluates the effect of GnRH (Gonadotropine Releasing Hormone) agonist administration on ICSI outcome in GnRH antagonist ovarian stimulation protocol in women with 2 or ...

objective: to compare the pregnancy outcomes achieved by in vitro fertilization (ivf) between minimal stimulation and conventional antagonist protocols in poor ovarian responders (pors). materials and methods: in this randomized controlled trial, 77 pors undergoing ivf were selected and divided into two groups. first group was the minimal stimulation group (n = 42) receiving 100 mg/day clomiphe...

Recent findings In random-start protocols, the number of total and mature oocytes retrieved, oocyte maturity rate, mature oocyte yield and fertilization rates are similar to those in conventional (early follicular phase start) protocols. Starting ovarian stimulation in the late follicular or luteal phase did not show any superiority against the other. The presence of corpus luteum or luteal pha...

background: c-reactive protein (crp) can be increased after hormonal stimulations. the changes of crp might affect the success of in-vitro fertilization (ivf). objective: the aim of this study was to determine the possible relationship between the serum crp level and outcome of controlled ovarian stimulation, and pregnancy rate in patients undergoing ivf or intra cytoplasmic sperm injection (ic...

ovarian hyperstimulation syndrome (ohss) is a unique iatrogenic complication of controlled ovarian stimulation (coh)/in vitro fertilization (ivf) in reproductive endocrinology occurring during the luteal phase or early pregnancy. it can have a serious impact on the patient�s health. with the expansion of the assisted reproductive techniques (art) from 1978, the incidence of ohss is increasing w...