نتایج جستجو برای: ototoxicity
تعداد نتایج: 1279 فیلتر نتایج به سال:
Forouzesh and colleagues recently reported an increase in vancomycin ototoxicity in parallel with the increasing use of higher vancomycin doses (4). The report suggests an overall incidence of vancomycin-induced ototoxicity of 12%, doubling historic estimates (3). This is a surprisingly high estimate for a drug that many experts do not consider to be ototoxic (5, 6). The authors have outlined s...
BACKGROUND Cisplatin is one of the most ototoxic chemotherapy drugs, resulting in a permanent and irreversible hearing loss in up to 50% of patients. Cisplatin and gentamicin are thought to damage hearing through a common mechanism, involving reactive oxygen species in the inner ear. Aspirin has been shown to minimise gentamicin-induced ototoxicity. We, therefore, tested the hypothesis that asp...
Forouzesh and colleagues recently reported an increase in vancomycin ototoxicity in parallel with the increasing use of higher vancomycin doses (4). The report suggests an overall incidence of vancomycin-induced ototoxicity of 12%, doubling historic estimates (3). This is a surprisingly high estimate for a drug that many experts do not consider to be ototoxic (5, 6). The authors have outlined s...
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