TOPIC: Lung Cancer TYPE: Medical Student/Resident Case Reports INTRODUCTION: metastases have been reported in over 40 percent of men with prostate cancer (1). One third to half patients metastasis at time presentation bone involvement 90 the cases. Prostate that metastasizes lungs without any is a rare occurrence (2). CASE PRESENTATION: A 75-year-old male veteran presented complaints hemoptysis...

Abstract Background Extraskeletal osteosarcoma (ESOS) is a rare mesenchymal malignancy, which produces osteoid, bone, or chondroid material and located in the soft tissue without attachment to skeletal bones periosteum. One of things that ESOS originated from mesentery much rarer. Case presentation A 75-year female had history pain left lower abdomen for more than 4 months. Abdominal computeriz...

UNLABELLED The combination of small-animal PET/CT scans and conventional imaging methods may enhance the evaluation of in vivo biologic interactions of murine models in the study of prostate cancer metastasis to bone. METHODS Small-animal PET/CT scans using (18)F-fluoride ion and (18)F-FDG coregistered with high-resolution small-animal CT scans were used to longitudinally assess the formation...

 Background: Osteopoikilosis (OPK) is a rare inherited condition of the bones, transmitted as an autosomal dominant trait characterized by numerous hyperostotic areas that tend to localize in periarticular osseous regions. It is usually asymptomatic and is often diagnosed incidentally during x-rays made by other reasons. We present a case of 34-year-old man suffering from polyarthralgia an...

AIMS To clarify the clinicopathological profile of osteosarcomas showing an intensely positive immunoreaction for cytokeratin. METHODS Clinicopathological and immunohistochemical features were analysed in 131 patients with non-metastatic, conventional osteosarcoma, treated in Akita University and National Cancer Centre in Tokyo between 1972 and 1999. RESULTS Six patients (4.5%; mean age, 32...

Tumor cells frequently have pronounced effects on the skeleton including bone destruction, bone pain, hypercalcemia, and depletion of bone marrow cells. Despite the serious sequelae associated with skeletal metastasis, the mechanisms by which tumor cells alter bone homeostasis remain largely unknown. In this study, we tested the hypothesis that the disruption of bone homeostasis by tumor cells ...

Malignancies may produce bony metastases which may be osteoclastic or osteoblastic. Vertebrae are a common site for bony metastases. Prostatic adenocarcinoma is an important source of vertebral metastases that are mainly osteoblastic in nature. As the osteoblastic metastases are developing there is an ongoing osteoclastic activity which is going on at the microscopic level. Presence of gross os...