patients and methods this retrospective cohort study included 405 renal transplant patients from kerman university of medical sciences hospital, kerman, iran from 2004 to 2010. kaplan-meier method was used to estimate survival rates of patients, and time-dependent cox regression was used to examine the effect of allograft failure on patient survival. results during 4.06 years (median) of follow...

Brucellosis, a frequent bacterial zoonosis, can produce debilitating chronic disease with involvement of multiple organs in human patients. Whereas acute brucellosis is well studied using the murine animal model, long-term complications of host-pathogen interaction remain largely elusive. Human brucellosis frequently results in persistent, chronic osteoarticular system involvement, with complic...

Dynamic modeling of osteoarticular system is necessary because the exertion of various actions and natural physiological movements are essentially dynamic. The wide mobility of human body leads to the necessity of modeling the osteoarticular system as a mechanism with a large number of degrees of freedom. The differential equations system obtained are very complex and assume numerical integrati...

Advantages of MALDI-TOF MS (MS) were evaluated for diagnosis of bone and joint infections after enrichment of synovial fluid (SF) or crushed osteoarticular samples (CSs). MS was performed after enrichment of SF or crushed osteoarticular samples CS (n = 108) in both aerobic and anaerobic vials. Extraction was performed on 113 vials (SF: n = 47; CS: n = 66), using the Sepsityper® kit prior identi...

Disseminated candidiasis in intravenous (IV) drug abusers is a distinctive syndrome. The hallmarks of this syndrome include the sequential development of skin, eye, and osteoarticular lesions; an epidemic nature in some cases; association with the use of brown heroin diluted with lemon juice; and the etiologic agent, which almost always is Candida albicans. In this case, a 42-year-old male IV d...

Despite advances in understanding and management, paediatric osteoarticular infections continue to pose diagnostic difficulties for clinicians. Delays in diagnosis can lead to potentially devastating morbidity.No single investigation, including joint aspiration, is sufficiently reliable to diagnose conclusively paediatric bone and joint infection. Diagnosis should be based on a combination of c...