Abstract Background Granulomatosis with polyangiitis (GPA) causes a recurring inflammation in nose and paranasal sinuses that clinically resembles chronic rhinosinusitis (CRS) of other aetiologies. While sinonasal is not among the life-threatening features GPA, patients report it to have major negative impact on quality life. A relatively large proportion GPA severe CRS extensive damage sinus s...

Accepted 24 October 1997 A 14-week-old girl was brought in with a history of painful swelling of both legs since the age of one month. The onset was insidious and was not associated with trauma or fall. There was no history of fever or associated constitutional symptoms. The birth history was normal and the infant was apparently asymptomatic until the age of one month. Examination revealed a he...

In 1835 Maisonneuve first recognized osteomyelitis as a complication of typhoid and since then this bone lesion, although well known, has been reported only occasionally. Murphy (1916) collected 164 cases of typhoid periostitis and osteitis occurring in 18,840 cases of typhoid infection reported by 15 authors, an incidence of 0 82% of bone involvement. Veal (1939) also found osteitis in less th...

The concept of osteoimmunology is based on growing insight into the links between the immune system and bone at the anatomical, vascular, cellular, and molecular levels. In both rheumatoid arthritis (RA) and ankylosing spondylitis (AS), bone is a target of inflammation. Activated immune cells at sites of inflammation produce a wide spectrum of cytokines in favor of increased bone resorption in ...

INTRODUCTION Cartilage damage impacts on patient disability in rheumatoid arthritis (RA). The aims of this magnetic resonance imaging (MRI) study were to investigate cartilage damage over three years and determine predictive factors. METHODS A total of 38 RA patients and 22 controls were enrolled at t = 0 (2009). After 3 years, clinical and MRI data were available in 28 patients and 15 contro...

BACKGROUND/AIM Alveolar osteitis (AO) is the extraction wound healing disorder with a presence of severe pain. Low level laser therapy stimulates cell metabolism and microcirculation, have has pronounced analgesic, antiedematous and anti-inflammatory effect and speeds up wound healing process. The aim of this study was to present results of clinical research that examined the effectiveness of l...

The morphological appearance of an osteoblast largely alters with its differentiation and maturation, along with the change of cell function. We quantitatively observed the osteoblast morphology and compared it with bone metabolism. Biopsied iliac bone samples obtained from 77 dialysis patients (14 mild change, 37 osteitis fibrosa, 2 osteomalacia, 8 mixed, and 16 adynamic bone) were included in...

OBJECTIVES MRI bone oedema has been observed in early and advanced RA and may represent a cellular infiltrate (osteitis) in subchondral bone. We studied MRI scans from RA patients undergoing surgery, seeking to identify regions of bone oedema and examine its histopathological equivalent in resected bone. METHODS Preoperative contrast-enhanced MRI scans were obtained in 11 RA patients schedule...

BACKGROUND The most common sequelae after surgical removal of mandibular third molar are pain, trismus, swelling, and dysphagia. However, these symptoms can also signal the onset of surgical site infection and alveoli osteitis. The aim of this study was to evaluate the efficacy of prophylactic amoxicillin/clavulanic acid and levofloxacin and preemptive therapy of amoxicillin/clavulanic acid in ...