As the support and stabilization of organ function is a major goal of treatment in the Intensive Care Unit (ICU), changes in the function of organ systems are an important indicator of the progression of the disease and recovery. This paper presents how to construct a model that describes changes in organ failure of ICU patients on a day-to-day basis. The model is based on the daily Sequential ...

The relative ease of identifying microRNAs and their increasing recognition as important regulators of organogenesis motivate the development of methods to efficiently assess microRNA function during organ morphogenesis. In this context, embryonic organ explants provide a reliable and reproducible system that recapitulates some of the important early morphogenetic processes during organ develop...

In a typical isolated organ perfusion experiment, a substance is injected upstream of an organ and then collected at some distance downstream. To reach the organ from the injection site, and then from the organ to the collector, a solute passes through catheters, usually tubes with circular cross-sections. Catheters cause distortion to the concentration-time profile of the perfusion. In this pa...

Several methods have been developed for generating 3D, in vitro, organ-on-chip models of human vasculature to study vascular function, transport, and tissue engineering. However, many these existing lack...

background kawasaki disease (kd) is a vasculitis affecting multi-organ systems including liver and kidneys. kd is diagnosed by some clinical criteria including sterile pyuria, microscopic hematuria, proteinuria due to renal involvement, liver abnormalities manifesting as abnormal liver function tests, gallbladder hydrops, and hypoalbuminemia. objectives the aim of the study was to determine the...

obesity is characterized as a state of systemic low-grade inflammation suggesting a link between metabolism and immune function. obesity has been shown to predispose individuals to an increased risk of many diseases.since 1980s, a threefold increase in obesity has been reported in much of the world.obesity is a result of energy imbalance. one of the components that control energy balance is adi...

THE pronephros of the chick is usually considered to be a vestigial organ. It only appears for a short period during early development and it is never functional as an excretory organ. From it, however, the primordium of the Wolffian duct is formed, by the confluence of the segmented pronephric tubules to a continuous strand of cells. This strand lengthens and extends into the posterior part of...

Implantable left-ventricular assist devices (LVAD) are successfully used as a bridge to transplant if the patient's condition is worsening and no donor organ is available. They allow recovery of compromised organ function. However, postoperative bleeding, thrombemboelism, and right-heart failure may jeopardize the important improvement of organ function and may even lead to death. We introduce ...

Anemia merupakan salah satu masalah yang banyak dialami anak dengan penyakit ginjal kronik. Banyak faktor berperan dalam timbulnya anemia pada Dampak kronik adalah menurunnya kualitas hidup, gangguan fungsi organ, dan meningkatnya mortalitas. Ada beberapa modalitas tata laksana is the most common problem in children with chronic kidney disease. Many factors contribute for risk The impact of on ...