AIM We hypothesised that chloral hydrate is safe and effective for sedation during dental treatments for children with mild asthma. We evaluated the safety and efficacy of chloral hydrate by measuring changes in heart rate (HR), transcutaneous oxygen saturation, (SpO2), asthma score, behaviour, types and frequency of adverse reactions associated with chloral hydrate were assessed throughout tre...

PURPOSE The purpose of this study was to compare the safety and efficacy of submucosal-administered meperidine (SM) and oral-administered meperidine (OM). Both regimens were used in conjunction with oral hydroxyzine for the sedation of children for dental treatment. METHODS Twenty preschool-age children, with previous histories of uncooperative behavior, were randomly assigned to first receiv...

BACKGROUND The safety profiles and efficacies of remifentanil and dexmedetomidine (a sedative-analgesic without respiratory depression) for sedation during flexible bronchoscopy were investigated. METHODS Seventy-two patients undergoing elective flexible bronchoscopy were randomly assigned to a propofol-remifentanil group (Group PR, n=36) or a propofol-dexmedetomidine group (Group PD, n=36). ...

Aims: Temporomandibular dysfunction is a generic term that covers large number of clinical problems affecting not only TMJ (Temporomandibular Joint), but also the masticatory musculature and related structures. Arthrocentesis most commonly used technique in patients with pain or limitation oral opening due to joint causes which conservative treatment has failed. It generally performed under loc...

Child visit to the dentist’s office can elicit fear and anxiety which can cause chaos to both the dentist and the child patient and, which in turn subvert the delivery of quality dental care, thus posing a challenge to oral health care practitioners worldwide. As pedodontists, our motto is to strive to relieve pain and suffering, and pledge to do no harm. Anxiety if not handled with tender love...

conclusions on the basis of our study, we conclude that nasal midazolam spray is acceptable and is a good alternative to oral midazolam as premedication in the pediatric population. objectives to compare the efficacy of midazolam administered orally and by intranasal spray, with the specific objective of assessing their efficacy in terms of acceptability to the patients, whether they achieve a ...

STUDY OBJECTIVE Fasting time before procedural sedation and analgesia in a pediatric emergency department (ED) was recently reported to have no association with the incidence of adverse events. This study further investigates preprocedural fasting and adverse events. METHODS Data were analyzed from a prospectively generated database comprising consecutive sedation events from June 1996 to Mar...

Purpose: The purpose of this study was to evaluate the cardiopulmonary effects of 2 sedation regimens during treatment: (1) oral meperidine and hydroxyzine with nitrous oxide (N20); and (2) oral diazepam and hydroxysine, submucosal meperidine, and NZO. Nitrous oxide was tapered to oxygen (0) only 10 minutes following submucosal meperidine administration. Methods: Sixty-two children were evaluat...

Benzodiazepine have been shown to suppress ventilatory responses to hyperoxic hypercapnia (HCVR) and isocapnic HVR when taken parenterally. Most patients would, however, prefer to take an oral rather than parenteral preparation but the effect of oral benzodiazepine on these ventilatory responses has not been well studied. We therefore studied the effect of oral midazolam (7.5 mg) and diazepam (...