The investment in small hydropower plants requires the analysis of hydrological, technical, operational, budgetary, economical and financial aspects. The analysis of each possible configuration demands the joint action of several technicians, consuming substantial time and money. During initial design of the project, simplified procedures are usually adopted which may compromise the quality of ...

In this work we apply the FDA proposed precision criteria necessary for pediatric pharmacokinetic studies (Wang et. al., 2012) as a stopping criteria for a model based adaptive optimal design (MBAOD) of an adult to children pharmacokinetic bridging study. We demonstrate the power of the MBAOD compared to both traditional designs as well as non-adaptive optimal designs.

This paper presents the design optimization of axial flux surface mounted Permanent Magnet Brushless DC motor based on genetic algorithm for an electrical vehicle application. The rating of the motor calculated form vehicle dynamics is 250 W, 150 rpm. The axial flux surface mounted Permanent Magnet Brushless DC (PMBLDC) motor was designed to fit in the rim of the wheel. There are several design...

We discuss the optimal design problem in regression models with long range dependence error structure. Asymptotic optimal designs are derived and it is demonstrated that these designs depend only indirectly on the correlation function. Several examples are investigated to illustrate the theory. Finally the optimal designs are compared with asymptotic optimal designs, which were derived by Bicke...