Optical coherence tomography (OCT) is an optical signal acquisition and processing method. It captures micrometer-resolution, three-dimensional images from within optical scattering media (e.g., biological tissue). Optical coherence tomography is an interferometric technique, typically employing near-infrared light. The use of relatively long wavelength light allows it to penetrate into the sca...

background:  optical coherence tomography (oct) is a non-invasive instrument, which can be used to estimate the thickness of the retinal nerve fibre layer (rnfl) and provides an indirect measurement of axonal destruction in multiple sclerosis (ms). the main aim of this study was to find out any correlations between p100 latency in visual evoked potential (vep) and rnfl thickness. methods: the p...

purpose: to describe the association between optic disc traction and non-arteritic anterior ischemic optic neuropathy (naion). methods: eighty three eyes of 83 patients with naion were evaluated by optical coherence tomography (oct) for detecting vitreous adhesion to the optic nerve head with separation from adjacent retina (partial posterior vitreous detachment). those who were negative for su...

Optical sectioning is instrumental for the observation of extended biological samples. It allows only a slice sample while rejecting contributions from out focus depths. The acquisition whole volume then requires an axial displacement or focus. To satisfy Nyquist sampling, this has to be equal half resolution. As lateral and resolutions are coupled by numerical aperture microscope objective in ...

Abstract Integrating all optical components of an coherence tomography (OCT) device into a single chip is non-trivial and challenging job. The design development such lab-on-a possible only via Micro-Opto-Electro-Mechanical System (MOEMS) technology. reproducible integrated fabrication would reduce cost size many folds as compared to bulk or fiber optic OCT system. A miniaturized less than 5mm ...

Optical coherence tomography angiography (OCTA) is a noninvasive approach that can visualize blood vessels down to the capillary level. With the advent of high-speed OCT and efficient algorithms, practical OCTA of ocular circulation is now available to ophthalmologists. Clinical investigations that used OCTA have increased exponentially in the past few years. This review will cover the history ...

ince intravascular ultrasound (IVUS) was introduced in the early 1990 s,1,2 it has been used not only as an adjunctive device to percutaneous coronary interventions (PCI), but also as a research tool to evaluate vessel structure in detail. Although IVUS has helped broaden our understanding of coronary artery structure, its limited spatial resolution does not allow for the assessment of microstr...

An experimental tracking optical coherence tomography (OCT) system has been clinically tested. The prototype instrument uses a secondary sensing beam and steering mirrors to compensate for eye motion with a closed-loop bandwidth of 1 kHz and tracking accuracy, to within less than the OCT beam diameter. The retinal tracker improved image registration accuracy to <1 transverse pixel (<60 microm)....

Imaging of a weak target hidden behind a scattering medium can be significantly confounded by glare. We report a method, termed coherence gated negation (CGN), that uses destructive optical interference to suppress glare and allow improved imaging of a weak target. As a demonstration, we show that by permuting through a set range of amplitude and phase values for a reference beam interfering wi...