to evaluate the effectiveness of a relapse prevention cognitive-behavioral model, based on marlatt treatment approach, in opioid-dependent patients participating in the methadone maintenance treatment (mmt) in iran.the study consisted of 92 individuals treated with methadone in iranian national center of addiction studies (incas). participants were randomized into two groups: educational interv...

Objective To compare the risk for all cause and overdose mortality in people with opioid dependence during and after substitution treatment with methadone or buprenorphine and to characterise trends in risk of mortality after initiation and cessation of treatment.Design Systematic review and meta-analysis.Data sources Medline, Embase, PsycINFO, and LILACS to September 2016.Study selection Prosp...

Editorials 83 The United Nations Office of Drugs and Crime in its 2012 World drug report estimates that 0.6% of the world's adult population – some 27 million people – are problem users of illicit drugs. 1 This represents about 10% of all people who used illicit drugs in 2011 and suggests that most people can use drugs recreationally without becoming dependent. What makes these 10% different is...

OBJECTIVE To investigate morbidity related to misuse of over-the-counter (OTC) codeine-ibuprofen analgesics. DESIGN AND SETTING Prospective case series collected from Victorian hospital-based addiction medicine specialists between May 2005 and December 2008. MAIN OUTCOME MEASURES Morbidity associated with codeine-ibuprofen misuse. RESULTS Twenty-seven patients with serious morbidity were ...

BACKGROUND Opioid substitution treatment (OST) is not uniformly provided in all prisons as recommended by international guidelines. The Swiss prison of Champ-Dollon in Geneva is an exception, where OST has been available for the last 20 years. The aims of this study were to describe the OST programme in this pretrial prison setting, and the patients involved. METHODS We reviewed health record...

Pain is the most feared symptom for patients diagnosed with cancer. Although our understanding of cancer pain and its management has greatly improved in the past decade, an unacceptably large proportion of patients still do not receive adequate pain relief. Before commencing any form of treatment, patients must receive a thorough assessment in order to define the pain, causes and severity. The ...