K(+) channels are differentially expressed throughout oligodendrocyte (Olg) development. K(V)1 family voltage-sensitive K(+) channels have been implicated in proliferation and migration of Olg progenitor cell (OPC) stage, and inward rectifier K+ channels (K(IR))4.1 are required for OPC differentiation to myelin-forming Olg. In this report we have identified a Shaw family K(+) channel, K(V)3.1, ...

Candida glabrata colonization is common in patients receiving radiation treatment for head and neck cancer, but to our knowledge has never been described as the infecting organism with oropharyngeal candidiasis (OPC). This study presents the first three patients described with C. glabrata OPC in this patient population. Patient 1 developed C. glabrata OPC and required fluconazole, 800 mg/day, f...

OBJECTIVE To examine if increased general practice activity is associated with lower outpatient specialist clinic use. DESIGN Cross-sectional population based study. SETTING All 430 Norwegian municipalities in 2009. PARTICIPANTS All Norwegians aged ≥65 years (n=721 915; 56% women-15% of the total population). MAIN OUTCOME MEASURE Specialised care outpatient clinic consultations per 1000...

Candida albicans is a causative agent of oropharyngeal candidiasis (OPC), a biofilm-like infection of the oral mucosa. Biofilm formation depends upon the C. albicans transcription factor Bcr1, and previous studies indicate that Bcr1 is required for OPC in a mouse model of infection. Here we have used a nanoString gene expression measurement platform to elucidate the role of Bcr1 in OPC-related ...

Thyroid hormone (3,5,3'-triiodo-l-thyronine or T3) exerts a pleiotropic activity during central nervous system development. Hypothyroidism during the fetal and postnatal life results in an irreversible mental retardation syndrome. At the cellular level, T3 is known to act on neuronal and glial lineages and to control cell proliferation, apoptosis, migration, and differentiation. Oligodendrocyte...

Dispersion management (DM), optical phase conjugation (OPC), and the combination of DM and OPC are promising techniques to compensate for optical signal distortion due to group velocity dispersion and nonlinear Kerr effects. The system performance improvement in DM links combined with OPC has been reported; however, the fixed residual dispersion per span (RDPS) usually used in these links restr...

Human oligodendrocyte progenitor cell (OPC) specification and differentiation occurs slowly and limits the potential for cell-based treatment of demyelinating disease. In this study, using FACS-based isolation and microarray analysis, we identified a set of transcription factors expressed by human primary CD140a(+)O4(+) OPCs relative to CD133(+)CD140a(-) neural stem/progenitor cells (NPCs). Amo...

ABSTRACT AAPSM masks require OPC correction through pitch in order to print a linear dark line response vs the design CDs. The masks also require correction for the clear intensity imbalance caused by the phased etched Qz wall edge. The clear intensity can be balanced by two approaches;(or a combination of the two) data biasing or wet undercut etching of the Qz etched opening. IC manufacturers ...