BACKGROUND The lack of an experimental animal model that can reliably mimic all stages of osteonecrosis of the femoral head has hindered progress toward the successful prevention and treatment of the disease. MATERIAL/METHODS A goat model of osteonecrosis of the femoral head (ONFH) was established and observed from the early to the intermediate-to-late stage of mechanical failure. Absolute al...

It is difficult to predict if and when the femoral head will collapse and whether the collapse can be minimized. This study examined the final outcome of early-stage osteonecrosis of the femoral head (ONFH) using magnetic resonance imaging to verify the relationship between preservation of the lateral pillar and collapse of the femoral head. A midcoronal section of the femoral head was divided ...

BACKGROUND Methylenetetrahydrofolate reductase (MTHFR) SNP rs1801133 has been frequently investigated in recent years. Relevant candidate gene association studies with this SNP and osteonecrosis of the femoral head (ONFH) reported conflicting results. Meta-analysis provides a method to combine these data and to determine the association in a larger sample size. METHOD We conducted a systemati...

Musculoskeletal complications following COVID-19 infection or because of its medications had been reported in the literature. Here, we report on seven hips four patients who presented with osteonecrosis femoral head (ONFH) after having infection, and their treatment regimen included glucocorticoid. Four to us complaining hip pain (bilateral three unilateral one), all being diagnosed as line man...

Introduction: There are many treatment options for patients who have osteonecrosis of the femoral head (ONFH) and management strategies vary widely both among within individual countries. Although researchers attempted to elucidate optimal managing this disease, lack large-scale randomized control trials agreement on disease staging curtailed development clear-cut guidelines. Materials Methods:...

Aims: This study aims to investigate the long-term results of vascularized iliac bone grafting (VIBG) for osteonecrosis femoral head (ONFH). The primary outcome is survivorship VIBG, using conversion total hip arthroplasty as an end-point. Secondly, this will also analyse patient or disease factors influencing VIBG. Methods: Forty-two patients (50 hips) underwent VIBG ONFH in our institute betw...

PURPOSE The purpose of this study is to compare the perioperative blood loss in primary non-cemented total hip arthroplasty (THA) performed for rapidly destructive coxarthrosis (RDC) with the perioperative blood loss in primary non-cemented THA for typical osteonecrosis of the femoral head (ONFH). MATERIALS AND METHODS From January 2000 to December 2013, 19 patients were diagnosed with RDC (g...

The present study aimed to identify microRNAs (miRNAs) from bone marrow mesenchymal stem cells (BMSCs) in a rat model of steroid-induced osteonecrosis of the femoral head (ONFH) using Affymetrix GeneChip®. Following identification of miRNAs, the present study aimed to elucidate the molecular mechanisms underlying steroid-induced ONFH. A total of six C57BL/6J mice were randomly divided into two ...

Early diagnosis of osteonecrosis the femoral head (ONFH) can inhibit progression and improve preservation. The radiograph difference between early ONFH healthy ones is not apparent to naked eye. It also hard produce a large dataset train classification model. In this paper, we propose Asymmetric-Sensitive Transformer (AsT) capture uneven development bilateral enable robust detection. Our detect...

BACKGROUND In young patients with osteonecrosis of the femoral head (ONFH), short-stem total hip arthroplasty (THA) could allow a potential advantage in preserving metaphyseal bone-stock, when revision surgery might become necessary. However, only a few studies have evaluated the outcome of short-stem THAs in ONFH. We reviewed the prospectively collected data of a cementless partial neck-retain...