BACKGROUND Although the first laparoscopic radical prostatectomy was performed in 1997, few midterm oncologic data have been published for the extraperitoneal procedure. OBJECTIVE To determine the oncologic outcome of extraperitoneal laparoscopic radical prostatectomy (ELRP). DESIGN, SETTING, AND PARTICIPANTS From 2000 to 2007, 1115 consecutive patients underwent ELRP for a localized prosta...

Intraperitoneal free cancer cells in gastric adenocarcinoma are associated with a poor outcome. However, the true prognostic value of intraperitoneal free cancer cells is still unclear, leading to a lack of consensus in the management of gastric cancer. The aim of the present study is to perform a systematic review and meta-analysis to analyze intraperitoneal free cancer cells-positive patients...

Introduction: Trials of laparoscopic surgery for colorectal cancer in elderly with co-morbidity are needed. The aim of the present study was to evaluate the oncologic outcome after laparoscopic resection for non-metastatic colorectal cancer within a fast-track regimen comparing patients > 75 years of age to patients < 75 years of age. Methods: A total of 55 patients were laparoscopically operat...

background: several studies have established that all nurses need continuing education, especially those who are working in oncology wards. in the current programs, there are just two general patterns for teaching: teacher-centered and student-centered patterns. in this study, the effect of teacher-centered (lecture) and student-centered (module) teaching methods in relation to safety standards...

Endoscopic forceps biopsy is essential before planning an endoscopic resection of upper gastrointestinal epithelial tumors. However, forceps biopsy is limited by its superficiality and frequency of sampling errors. Histologic discrepancies between endoscopic forceps biopsies and resected specimens are frequent. Factors associated with such histologic discrepancies are tumor size, macroscopic ty...

PURPOSE We evaluate the operative outcome and oncologic outcome of laparoscopic liver resection for hepatocellular carcinoma (HCC), and compare with open liver resection. METHODS From January 2004 to December 2012, clinical data of 70 patients who underwent laparoscopic liver resection for HCC (laparoscopic liver resection group, lapa-group) were collected and analyzed retrospectively. Contro...

ZEB1, a member of the zinc-finger E-box binding homeobox family, is considered to play a crucial role in cancer progression and metastasis. In the current study, we investigated the role of ZEB1 in metastasis and chronic chemoresistance of epithelial ovarian carcinoma (EOC) cells. Using several EOC and acquired paclitaxel (PTX)-resistant EOC cell lines, we investigated whether silencing ZEB1 le...