For a long time lung cancer was associated with a fatalistic approach by healthcare professionals. In recent years, advances in imaging, improved diagnostic techniques and more effective treatment modalities are reasons for optimism. Accurate lung cancer staging is vitally important because treatment options and prognosis differ significantly by stage. The staging algorithm should include a con...

UNLABELLED Under Medicare's Coverage with Evidence Development policy, PET using (18)F-sodium fluoride (NaF PET) to identify osseous metastasis became a covered service if prospective registry data were collected. The National Oncologic PET Registry (NOPR) developed a NaF PET registry built on the foundation of its prior registry for PET with (18)F-FDG. Men with prostate cancer represented 72% ...

BACKGROUND There is as yet limited evidence about fertility-sparing surgery for early ovarian cancer (EOC) carried out laparoscopically. We sought to analyze recurrence patterns and fertility outcome in a cohort of ovarian cancer patients who underwent fertility-saving laparoscopic surgical staging. METHODS We conducted a retrospective analysis of prospectively collected data on all patients ...

Cancers of the uterine corpus and cervix are the most common gynecologic malignancies worldwide. The International Federation of Gynecology and Obstetrics (FIGO) staging system was first established in 1958, when it was recognized that the recurrence rate and patient outcomes were directly related to the degree of tumor spread at the patient's initial presentation. Changes in understanding of t...

background: differentiation between the muscularis mucosae (mm) and muscularispropria (mp) of the bladder remains challenging. objective: to identify mm- and mp-specific antigens that could be of potential value for staging of urothelialcarcinomain a pilot study. method: the expression of 12 protein antigens in 11 human bladder specimens was examined. there were 5 post radical cystectomy specim...

Patients with oncologic disease require frequent imaging tests (predominantly computed tomography) for follow-up. These patients may have thoracic vascular disease that can influence the diagnosis, treatment, and prognosis of their cancer. Primary vascular tumors can involve the thoracic vessels, like the pulmonary arteries (pulmonary artery sarcoma), and the neoplastic disease can extend local...

The transmembrane glycoprotein adhesion molecule CD146 is overexpressed in a wide variety of cancers. expression constitutes marker poor prognosis and correlates with cancer progression. Through molecular imaging, specific biomarker's distribution can be viewed vivo non-invasively. Radionuclide-labeled monoclonal antibodies or relevant fragments that target may find potential applications there...

PET/MRI is a relatively recent diagnostic tool for the evaluation of oncologic disease. It combines the excellent soft tissue contrast of MRI with the physiologic data regarding glucose metabolism of PET. It has been described that ADC values may be useful in oncologic imaging, with development of central necrosis within a malignancy corresponding with increased ADC values. It has long been kno...