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Q-ball imaging (QBI) is a high angular resolution diffusion imaging (HARDI) technique which has been proven very successful in resolving multiple intravoxel fiber orientations in MR images. The standard computation of the orientation distribution function (ODF, the probability of diffusion in a given direction) from q-ball data uses linear radial projection, neglecting the change in the volume ...
Fiber orientation is the key information in diffusion tractography. Several deconvolution methods have been proposed to obtain fiber orientations by estimating a fiber orientation distribution function (ODF). However, the L 2 regularization used in deconvolution often leads to false fibers that compromise the specificity of the results. To address this problem, we propose a method called diffus...
How to estimate the diffusion Ensemble Average Propagator (EAP) from the DWI signals in q-space is an open problem in diffusion MRI field. Many methods were proposed to estimate the Orientation Distribution Function (ODF) that is used to describe the fiber direction. However, ODF is just one of the features of the EAP. Compared with ODF, EAP has the full information about the diffusion process ...
The anisotropic elastic constants of human cortical bone were predicted using a specimen-specific micromechanical model that accounted for structural parameters across multiple length scales. At the nano-scale, the elastic constants of the mineralized collagen fibril were estimated from measured volume fractions of the constituent phases, namely apatite crystals and Type I collagen. The elastic...
IL-17 is a newly discovered T cell-derived cytokine whose role in osteoclast development has not been fully elucidated. Treatment of cocultures of mouse hemopoietic cells and primary osteoblasts with recombinant human IL-17 induced the formation of multinucleated cells, which satisfied major criteria of osteoclasts, including tartrate-resistant acid phosphatase activity, calcitonin receptors, a...
Effects of electroshock treatment (EST) on the microstructural evolution and mechanical properties near-β titanium alloy (Ti-55531) formed by directed energy deposition (DED) was studied in this work. With increase EST time, average hardness specimen decreased from 426 HV to 316 HV, fracture strain increased significantly, which attributed uniform dispersion α phase along grain boundaries insid...
OBJECTIVE To perform a comparative study of the cellular proliferation in the peripheral and central fibromas. MATERIAL AND METHODS Immunohistochemistry for PCNA and the AgNOR technique were performed in 9 cases of peripheral odontogenic fibroma (POF), in 4 cases of odontogenic fibroma (OdF), in 8 cases of peripheral ossifying fibroma (PEOF) and 7 cases of ossifying fibroma (OsF). The Kruskal...
Introduction. Diffusion-weighted (DW) MRI provides important information regarding the arrangement of white matter fibres. However, imperfections in the DW gradients may cause errors in the estimation of diffusion parameters. The sources of the gradient errors are various and may arise from long-term eddy currents, background gradients, imaging gradients, and spatial non-linearity and non-unifo...
PURPOSE To develop a bootstrap method to assess the quality of High Angular Resolution Diffusion Imaging (HARDI) data using Q-Ball imaging (QBI) reconstruction. MATERIALS AND METHODS HARDI data were re-shuffled using regular bootstrap with jackknife sampling. For each bootstrap dataset, the diffusion orientation distribution function (ODF) was estimated voxel-wise using QBI reconstruction bas...
High angular resolution diffusion imaging (HARDI) permits the computation of water molecule displacement probabilities over a sphere of possible displacement directions. This probability is often referred to as the orientation distribution function (ODF). In this paper we present a novel model for the diffusion ODF namely, a mixture of von Mises-Fisher (vMF) distributions. Our model is compact ...
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