Glaucoma, Pathological Myopia (PM), and Age-related Macular Degeneration (AMD) are three leading ocular diseases worldwide. Visual features extracted from retinal fundus images have been increasingly used for detecting these three diseases. In this paper, we present a discriminative feature selection model based on multi-task learning, which imposes the exclusive group lasso regularization for ...

Recent advances have suggested that long noncoding RNAs (lncRNAs) are differentially expressed in ocular tissues and play a critical role in the pathogenesis of different types of eye diseases. Here, we summarize the functions and mechanisms of known aberrantly-expressed lncRNAs and present a brief overview of relevant reports about lncRNAs in such ocular diseases as glaucoma, proliferative vit...

BACKGROUND In our earlier genome-wide association study on Stevens-Johnson Syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), we found that in Japanese patients with these severe ocular surface complications there was an association with prostaglandin E receptor 3 (EP3) gene (PTGER3) polymorphisms. We also reported that EP3 is dominantly expressed in the ocular surface-, e...

The trigeminal nerve gives rise to the corneal subbasal system, which plays a crucial role in sensations of touch, pain, and temperature ocular healing processes. Technological advancements instruments, particular vivo confocal microscopy aethesiometry, have allowed for structural functional evaluation nerves health disease. Through application these technologies humans animal models, abnormali...