This article presents the results of a study of the efficiency of silanation process of calcium phosphate glasses particles and its effect on the bioactivity behavior of glass- poly(methyl methacrylate) (PMMA) composites. Two different calcium phosphate glasses: 44.5CaO-44.5P2 O5 -11Na2 O (BV11) and 44.5CaO-44.5P2 O5 -6Na2 O-5TiO2 (G5) were synthesized and treated with silane coupling agent. Th...

We study the IIB engineering of N=1 gauge theories with unitary gauge group and matter in the adjoint and (anti)symmetric representations. We show that such theories can be obtained as Z2 orientifolds of certain Calabi-Yau A2 fibrations, and discuss the explicit T-duality transformation to an orientifolded Hanany-Witten construction. The low energy dynamics is described by a geometric transitio...

L-Rhamnose (L-Rha) is a component of the lipopolysaccharide (LPS) core, several O antigen polysaccharides, and the cell surface surfactant rhamnolipid of Pseudomonas aeruginosa. In this study, four contiguous genes (rmlBDAC) responsible for the synthesis of dTDP-L-Rha in P. aeruginosa have been cloned and characterized. Non-polar chromosomal rmlC mutants were generated in P. aeruginosa strains ...

BACKGROUND It is well known that the naturally occurring modified triterpenes in plants have a wide diversity of chemical structures and biological functions. The lupane-, oleanane-, and ursane-type triterpenes are the three major members of natural triterpenes with a wide range of biological properties. A systematic approach is necessary to review their structures and biological activities acc...

We report results from combined quantum mechanical/molecular mechanical (QM/MM) free energy simulations to explore metal-assisted phosphoryl transfer and general acid catalysis in the extended hammerhead ribozyme. The mechanisms considered here assume that the 2′OH group of C17 has already been activated (i.e., is deprotonated) and acts as a nucleophile to go on an inline attack to the adjacent...

High-pressure single crystal X-ray diffraction studies of a natural chondrodite, Mg4.76Fe0.22Ti0.02Si1.99O8 (OH1.26F0.74), and a synthetic OH-chondrodite, Mg4.98Si2.01H2.00O10, were performed using a diamond anvil cell (DAC) up to 7.3 and 5.9 GPa, respectively and at room temperature. FT-IR spectra of the natural chondrodite under high-pressure conditions up to 9.9 GPa was also observed using a...

When verotoxin (VT)-producing attaching and effacing Escherichia coli (AEEC, serotype O5: H-) were inoculated perorally into 10-day-old rabbits, attaching of the E. coli to enterocytes and effecting of their microvillous portion were observed extensively from the ileum to the colon. Subsequent apoptotic changes of the infected enterocytes were demonstrated by the terminal deoxynucleotidyl trans...