نتایج جستجو برای: o2 desaturation

تعداد نتایج: 28286  

Journal: :Journal of Oral and Maxillofacial Surgery 2021

Purpose In anesthetic management, it is widely accepted that obese patients are more likely to suffer airway obstructions and reductions in arterial oxygen saturation (SpO2). Therefore, important take special measures prevent desaturation during the deep sedation of patients. This clinical study examined whether use nasal high-flow systems (NHFS) keep higher SpO2 reduced hypoxemia than conventi...

Journal: :British Journal of Anaesthesia 2010

Journal: :Stroke 2006
Deborah J C Ramsey David G Smithard Lalit Kalra

BACKGROUND AND PURPOSE Desaturation during swallowing may help to identify aspiration in stroke patients. This study investigated pulse oximetry, bedside swallowing assessment (BSA), and videofluoroscopy as tests for detecting aspiration after stroke. METHODS Swallowing was assessed in 189 stroke patients (mean+/-SD age, 70.9+/-12.3 years) within 5 days of symptom onset with a modified BSA (w...

2017
Raylene Dias Nandini Dave Rachana Chhabria Harick Shah Madhu Garasia

BACKGROUND AND AIMS Neonates and infants are prone to oxygen desaturation during the induction of general anaesthesia. Pharyngeal oxygen insufflation has been shown to delay the onset of desaturation and hypoxaemia during apnoea. We tested the hypothesis that deep laryngeal oxygenation with Oxiport® Miller blade would delay the onset of desaturation compared to laryngoscopy without supplemental...

2014
Changhwan Kim Yong Bum Park So Young Park Sunghoon Park Cheol-Hong Kim Sang Myeon Park Myung-Goo Lee In-Gyu Hyun Ki-Suck Jung Dong-Gyu Kim

PURPOSE A recent study demonstrated that exertional desaturation is a predictor of rapid decline in lung function in patients with chronic obstructive pulmonary disease (COPD); however, the study was limited by its method used to detect exertional desaturation. The main purpose of this study was to explore whether exertional desaturation assessed using nadir oxygen saturation (SpO₂) during the ...

Journal: :American journal of respiratory and critical care medicine 2009
Paul E Peppard Neil R Ward Mary J Morrell

RATIONALE Obesity increases the risk and severity of sleep-disordered breathing. The degree to which excess body weight contributes to blood oxygen desaturation during hypopneic and apneic events has not been comprehensively characterized. OBJECTIVES To quantify the association between excess body weight and oxygen desaturation during sleep-disordered breathing. METHODS A total of 750 adult...

2012
Rajesh Kumar Lam-Son Phan Tran Anjanasree K. Neelakandan Henry T. Nguyen

BACKGROUND Synthesis of polyunsaturated fatty acids (PUFAs) in the endoplasmic reticulum of plants typically involves the fatty acid desaturases FAD2 and FAD3, which use cytochrome b(5) (Cb5) as an electron donor. Higher plants are reported to have multiple isoforms of Cb5, in contrast to a single Cb5 in mammals and yeast. Despite the wealth of information available on the roles of FAD2 and FAD...

Journal: :Thorax 2009
C A Lewis W Fergusson T Eaton I Zeng J Kolbe

BACKGROUND AND AIMS The clinical impact of nocturnal desaturation on health related quality of life (HRQL) and sleep in chronic obstructive pulmonary disease (COPD) has been little studied. The aim of this study was to evaluate the prevalence and clinical impact of nocturnal desaturation in a typical outpatient population with COPD. PATIENTS AND METHODS Between 2002 and 2005, consecutive pati...

Journal: :Cancer research 2013
Kevin J Williams Joseph P Argus Yue Zhu Moses Q Wilks Beth N Marbois Autumn G York Yoko Kidani Alexandra L Pourzia David Akhavan Dominique N Lisiero Evangelia Komisopoulou Amy H Henkin Horacio Soto Brian T Chamberlain Laurent Vergnes Michael E Jung Jorge Z Torres Linda M Liau Heather R Christofk Robert M Prins Paul S Mischel Karen Reue Thomas G Graeber Steven J Bensinger

The sterol regulatory element-binding proteins (SREBP) are key transcriptional regulators of lipid metabolism and cellular growth. It has been proposed that SREBP signaling regulates cellular growth through its ability to drive lipid biosynthesis. Unexpectedly, we find that loss of SREBP activity inhibits cancer cell growth and viability by uncoupling fatty acid synthesis from desaturation. Int...

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