GQM+Strategies is an approach that aligns the business goals at each level of an organization to strategies to achieve overall business goals and assesses the achievement of such goals. Strategies are extracted from business goals based on rationales (contexts and assumptions). Using the proposed approach, which refines the GQM+Strategies model by extracting rationales based on the analysis of ...

Our review focuses on the colonic macrophage, a monocyte-derived, tissue-resident macrophage, and the role it plays in health and disease, specifically in inflammatory conditions such as inflammatory bowel disease and cancer of the colon and rectum. We give special emphasis to macrophage polarization, or phenotype, in these different states. We focus on macrophages because they are one of the m...

Nanoencapsulation is commonly used to improve nutritional properties, rheological behavior and flavor profile of phytochemicals. The particles commonly utilized to encapsulate the functional ingredients are natural polymers such as polysaccharides and proteins. There is an ever-growing interest for use of polysaccharides to encapsulate hydrophobic phytochemicals like curcumin. Curcumin is a pol...

diabetic macular edema (dme) is a leading cause of vision loss in the working-age population worldwide. numerous early studies suggest an important role for intravitreal anti-vegf agents such as bevacizumab in the management of dme. we reviewed manuscripts that had investigated pharmacokinetic, efficacy, safety, dose and frequency of intravitreal bevacizumab (ivb) injections as well as effect o...

Developing reliable and eco-friendly processes for the synthesis of metallic nanoparticles is an essential step in the field of application of nanotechnology .Using natural factories such as biological systems is a way of developing such processes. Nowadays, the synthesis of silver nanoparticles is very common due to its numerous applications in different fields. The synthesis of these nanopart...