Nrf2:INrf2 (Keap1) are cellular sensors of chemical- and radiation-induced oxidative and electrophilic stress. Nrf2 is a nuclear transcription factor that controls the expression and coordinated induction of a battery of defensive genes encoding detoxifying enzymes and antioxidant proteins. This is a mechanism of critical importance for cellular protection and cell survival. Nrf2 is retained in...

The transcription factor Nrf2 has emerged as a master regulator of cellular redox homeostasis. As an adaptive response to oxidative stress, Nrf2 activates the transcription of a battery of genes encoding antioxidants, detoxification enzymes, and xenobiotic transporters by binding the cis-antioxidant response element in the promoter regions of genes. The magnitude and duration of inducible Nrf2 ...

......................................................................................ii Declaration of Originality..................................................................iii Table of

background: the earlier atomic bomb explosion in hiroshima and nagasaki, and three worth mentioning nuclear accidents - detonation at fukushima daiichi nuclear plant, chernobyl nuclear fallout and an accident at three mile island nuclear power plant have made us more worried about the secure exploitation of nuclear energy. the central focus of this paper is to review radiation-mediated health e...

the main objective of this article is to examine the u.s. nuclear war plans, which have led to the transformation of the grand strategy of the united states since 1945, and they have also a significant impact on the nuclear programs of the nuclear – weapon states (nws), defense policies of nato and international security. research questions include: what are the similarities and differences in ...

a study of the kinetic analysis of total lead from spent car battery ash by hydrochloric acidleaching has been examined. the physico-chemical analysis of the ash powder was carried outby the inductively coupled plasma-mass spectrometry (icp-ms) and x–ray diffraction (xrd).the effects of the acid concentration, temperature and particle size on the rate of battery ashdissolution have been investi...

The untimed power failure is one of major issues confronting the successful commercialization of battery powered electric cars. So, an intelligent model predictive controller which adaptively schedules the load according to the predicted remaining charge of the Electric Vehicles(EV) battery saves the energy content of the battery and ensures the safe state of the Electric Vehicle. The most impo...

To reduce the imbalance of Smart Battery and prolong the life of Smart Battery, the smart battery management system equalization charging protection system of battery series is designed. The imbalance reason of Li-Ion battery series and common balance technology was firstly analyzed, and then the battery balance principle based on X3100 chip was analyzed, and smart battery balance control circu...

in the framework of non-proliferation treaty (npt) it has been enumerated three objectives as follow: 1) peaceful use of nuclear energy; 2) non-proliferation of nuclear weapons and 3) nuclear disarmament. the writers in this article have studied and analyzed multilateral aspects of the right of peaceful use of nuclear energy, and interpretation of some npt articles (1, 2 and 4).in the conclusio...