Background: To evaluate the role of 3D, 4D and color Doppler ultrasound (US) in the assessment of early human development. Materials and Methods: 380 women with uncomplicated early pregnancy between 5 and 14 weeks were evaluated by 3D, 4D and color Doppler US. Results: Regression analysis revealed exponential rise of the gestational sac volume with gestational age throughout the first trimester...

Background: Prenatal diagnosis for Fetal Chromosomal anomalies currently relies on assessment of risk followed by a combination of biochemical and nuchal translucency. Trisomy 21 is the most common trisomy that is associated with intellectual disability. Pregnant women who receive a prenatal diagnosis of trisomy 21 currently have the option of continuing or terminating their pregnancy, but no f...

A nuchal fibroma is a rare benign mass; it is a fibrolipoma-like soft tissue mass, usually located in the lower back and the neck. Males are affected far more often than females. It can occur extranuchally. It is a slow growing tumor and usually asymptomatic. We present a rare case of a 39-year old female who was diagnosed with nuchal-type fibroma on final pathology. The proper management for t...

The authors consider the possibility of using color Doppler of the ductus venosus and the measurement of nuchal translucency as a screening test for alterations in fetal cardiac functions in the first trimester of gestation. Review of the literature suggests that the combination of the ultrasonographic measurement of nuchal translucency and Doppler at 10 and 14 weeks of gestation can be effecti...

Objectives: To evaluate and compare the performance of various quality control methods for nuchal translucency (NT) measurements. Methods: Fetal NT measurements performed over a oneyear period in a single center were used for the study. The retrospective quality review methods proposed by the Fetal Medicine Foundation (FMF) and the Woman & Infants Hospital of Rhode Island (WIHRI) were assessed ...

OBJECTIVE To determine the relative contribution of nuchal translucency (NT) to the biochemical detection rates of combined screening for trisomies 13 and 18 in two healthcare systems practicing different quality-control systems of nuchal measurement. METHODS De-identified data collected from the Fetal Medicine Foundation in the United Kingdom and laboratory data from NTD laboratories in the ...

The nuchal translucency (NT) scan provides an opportunity to examine fetal anatomy. Current opinion on the advantages and limitations of assessing fetal anatomy at this early gestation is divided. Two case studies from our centre will be presented where assessing fetal anatomy was of great benefit - one in finding abnormalities, the other in excluding them. These cases along with review of the ...

Johnson, S. (1996). Down’s syndrome screening in the UK, Lancet, 347, 906–907. Pandya, P.P., Snijders, R.J.M., Johnson, S.P., de Loudes Brizot, M., Nicolaides, K.H. (1995). Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10 to 14 weeks of gestation, Br. J. Obstet. Gynaecol., 102, 957–962. Schuchter, K., Wald, N.J., Hackshaw, A.K., Hafner, E., Liebhardt, ...

Nuchal-type fibroma is a rare, benign, fibrous, tumor-like proliferation characterized by dense hypocellular bundles of collagen, with sparsely scattered fibroblasts, interspersed fat tissue, and entrapped nerve fibers. It usually develops in the posterior neck as a solitary, firm, poorly circumscribed, subcutaneous mass. Herein, we report about a 32-year-old man who presented with a 6-year his...