BACKGROUND Successful therapy of chronic hepatitis B with nucleos(t)ide analogues (NUCs) has been defined by undetectable HBV-DNA determined with conventional PCR (lower limit of detection (LLD) 60-80 IU/mL) in clinical registration trials. However, current EASL guidelines recommend highly sensitive real-time PCR (LLD<10-20 IU/mL) and define treatment response by HBV-DNA<10 IU/mL. AIM We eval...

1. Introduction With the rapid growth of various wireless services and applications calling for high data rate transmission there is a demand for developing robust wideband wireless technology. In order to counter count adverse phenomena such as multi-path signal propagation and interference, which become more pronounced in wideband systems, smart antennas can be employed as a remedy. So far, m...

The purpose of the study – to assess disorders’ degree endothelium dysfunction inpatients with nonspecific ulcerative colitis (NUC) and Crohn's disease (CD), dependingon severity inflammation.Material methods. 34 patients NUC 18 people CD continuousrecurrent courses, 15 in remission wereobserved. control group included 30 healthy volunteers.Results. It has been established that active had a sig...

We present a simple model for the host mass dependence of galaxy nucleation fraction ($f_{nuc}$), galaxy's nuclear star cluster (NSC) and in its surviving globular clusters ($M_{GC,obs}$). Considering orbital evolution GC potential, we define critical limit ($M_{GC,lim}$) above which can simultaneously in-spiral to centre due dynamical friction survive tidal dissolution, build up NSC. The analy...

The paper appraised the procedures involved in development of academic programmes Nigerian Universities and associated Quality Assurance measures by National Commission (NUC). It specifically examined roles Academic Planning Unit, Resource Verification regular Programme Accreditation exercises as critical quality assurance NUC to ensure institutions. challenges with effective implementation str...

The activity-regulated cytoskeleton associated protein Arc is strongly and quickly upregulated by neuronal activity, synaptic potentiation and learning. Arc entry in the synapse is followed by the endocytosis of glutamatergic AMPA receptors (AMPARs), and its nuclear accumulation has been shown in vitro to result in a small decline in the transcription of the GluA1 subunit of AMPARs. Since these...

Microscopy is an essential tool for the observation of microbial effectors in host cells. Manual evaluation of the acquired image data is elaborate and error prone. Thus, in order to increase objectivity and reproducibility of results, an automated evaluation of the experiment is performed. The present study evaluates methods to delineate HeLa cells depicted in phase-contrast (PC) micrographs, ...

BACKGROUND/AIMS Relapse has been reported after stopping nucleos(t)ide (NUC) therapy in the majority of chronic HBeAg negative hepatitis patients. However, the ideal treatment duration of HBeAg negative chronic hepatitis B (CHB) is not well known. We investigated the frequency of relapse in HBeAg negative CHB patients receiving NUC therapy. METHODS The NUC therapy was discontinued at least 3 ...

Bu çalışmada, Isparta ilinde satışı yapılan Tulum peyniri örneklerinde Staphylococcus aureus yayğınlığının tespiti ve S. izolatlarında antibiyotik direnç profillerinin genlerinin belirlenmesi amaçlanmıştır. 75 örneğinden toplam 141 muhtemel kolonisi izole edilmiştir. Gram boyama katalaz testi sonucu izolatların 100’ünün pozitif kok morfolojisinde özellik gösterdiği tespit türü üyesi olup olmadı...

To gain insight into the inability of newborns to mount efficient Th1 responses, we analyzed the molecular basis of defective IL-12(p35) expression in human neonatal monocyte-derived dendritic cells (DCs). Determination of IL-12(p35) pre-mRNA levels by real-time RT-PCR revealed that transcriptional activation of the gene in lipopolysaccharide-stimulated neonatal DCs was strongly impaired compar...