نتایج جستجو برای: noxious animals

تعداد نتایج: 217836  

Journal: :Pain 2008
Stefan Lautenbacher Miriam Kunz Simone Burkhardt

A few experimental observations have suggested that diffuse noxious inhibitory control (DNIC)-type inhibition acts preferentially on the pain system if this is in a sensitised state, e.g. after slow temporal summation (wind-up). However, firm evidence is still missing. Furthermore, sex-related factors, which seem to affect temporal summation as well as DNIC effects, might thus also modulate the...

2012
Juerg Schliessbach Eveline van der Klift Andreas Siegenthaler Lars Arendt-Nielsen Michele Curatolo Konrad Streitberger

Diffuse noxious inhibitory control (DNIC) is described as one possible mechanism of acupuncture analgesia. This study investigated the analgesic effect of acupuncture without stimulation compared to nonpenetrating sham acupuncture (NPSA) and cold-pressor-induced DNIC. Forty-five subjects received each of the three interventions in a randomized order. The analgesic effect was measured using pres...

Journal: :Bulletin of informatics and cybernetics 2004

Journal: :Proceedings for Annual Meeting of The Japanese Pharmacological Society 2018

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2015
Philip J Summers Robert M Layne Amanda C Ortega Gareth P Harris Bruce A Bamber Richard W Komuniecki

UNLABELLED Sensory inputs are integrated extensively before decision making, with altered multisensory integration being associated with disorders such as autism. We demonstrate that the two C. elegans AIB interneurons function as a biphasic switch, integrating antagonistic, tonic, and acute inputs from three distinct pairs of sensory neurons to modulate nociception. Off food, animals reverse a...

ژورنال: طب جنوب 2019
Movahed , Ali, Sadeghi , Mehdi, Vahedi Moghadam , Afsaneh,

Background: Portulaca Oleracea is a medicinal plant with many effects including analgesic and anti-inflammatory properties. This study aimed to investigate the effect of alcoholic extract of Portulaca Olerecea on CCI model of neuropathic pain (Bennet & Xie model) and acute thermal pain induced by Tail Flick. Materials and Methods: Adult male Wistar rats weighing 200-250 g were used. Sensitivity...

Introduction: This study aimed to examine the effects of induced inflammatory tooth pain on anxiety level in adult male rats. Methods: The mandibular incisors of 56 adult male rats were cut off and prefabricated crowns were fixed on the teeth. Formalin and capsaicin were injected intradentally to induce inflammatory tooth pain. Diazepam treated group received diazepam 30 minutes...

Journal: :medical journal of islamic republic of iran 0
e soleiman-nejad from the dept. of physiology. faculty of medicine. army university of medical sciences. po. box: 14185- 611. tehran y fathollahi the dept. of physiology. school a/medical sciences. tarbiat modarres university. po. box: 14115-111. tehran. s semnanian the institute of biochemistry and biophysics. tehran university. po.box: 13145-1384. tehran.l.r. iran.

the effects of formalin as a peripheral noxious stimulus on the activity of lateral paragigantocellularis nucleus (lpgi) neurons were examined. spontaneous activity oflpgi neurons was recorded after confirmation of their responsiveness to acute pain, and thereafter formalin (50 µl, 2.5%) was injected in the contralateral hindpaw. the response of the lpgi neurons was monitored for 60 min. a biph...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1978
J W Holaday E Wei H H Loh C H Li

Administration of the opiate antagonist naloxone to rats after acute or chronic heat exposure precipitates an increase in colonic temperature, an increase in escape attempts, and a decrease in body weight. These changes are accompanied by signs associated with hyperthermia such as salivation, diarrhea, and an abnormal extended posture. Although brain endorphin involvement is possible, hypophyse...

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