Abstract Background Hypertrophic cardiomyopathy (HCM) is a common inherited disease almost invariably caused by mutations in sarcomeric genes. The HCM phenotype clinically heterogeneous with myocyte hypertrophy, disarray, and myocardial fibrosis as histological hallmarks. This condition recognized an important cause of sudden cardiac death (SCD) the youth heart failure (HF) elderly. Current gui...