Microspheres are multiparticulate drug delivery systems that designed to deliver drugs a particular location at fixed rate. free-flowing powders made up of biodegradable proteins or synthetic polymers with particle sizes ranging from 1 1000µm. Benefits the use microspheres in fields such as delivery, bone tissue manufacturing, and absorption desorption contaminants by regeneration. The study sh...

Most common methods of delivery include the preferred topical (skin), transmucosal (nasal, buccal, sublingual, vaginal, ocular and rectal) inhalation routes. The conventional dosage forms provide drug release immediately it causes fluctuation level in blood depending upon form. Therefore to maintain concentration within therapeutically effective range needs novel system. In past few decades, co...

this review presents a brief outline of our current knowledge of the structure and chemical composition of the outer membrane vesicles (omvs), originating from the surface of gram negative bacteria including their outer membrane proteins and lipopolysaccharides. moreover, the functional roles and applications of omvs in medical research such as omv-based vaccines, omv adjuvants properties, omv ...

intravitreal injection is the most common approach for drug delivery to the posterior segment in humans. however, following the injection, drugs are rapidly eliminated from the vitreous, with half-lives up to a few days. depending on the rate of clearance from the vitreous, large boluses and frequent administrations may be required to ensure therapeutic levels over an extended period of time. m...

objective(s): in this research, zeolite x and zeolite y were used as vehicle to prepare intestine targeted oral delivery systems of indomethacin and ibuprofen. materials and methods: a soaking procedure was implemented to encapsulate indomethacin or ibuprofen within synthetic zeolites. gravimetric methods and ir spectra of prepared formulations were used to assess drug loading efficiencies into...