نتایج جستجو برای: novel coronavirus
تعداد نتایج: 828555 فیلتر نتایج به سال:
[no abstract available]
The outbreak of a novel coronavirus, referred to as coronavirus disease-19 (COVID-19), with its sentinel case in Wuhan,China, in December 2019, has spread rapidly around the globe. On March 11, 2020, the World Health Organization(WHO) declared COVID-19 a worldwide pandemic, which led to most countries implementing social distancingprotocols. Most non-essential medical practice...
A novel coronavirus 2019 (Covid-19) was identified in Wuhan, China causing an outbreak of pneumonia worldwide. The first infection of the coronavirus was associated with a kind of seafood. The patient of the covid-19 pandemic was accompanied by the most common symptoms of fever, lung inflammation, dry cough, and tiredness. Researchers have found that natural flavonoid and antioxidant products s...
The drastic increase in the number of coronaviruses discovered and coronavirus genomes being sequenced have given us an unprecedented opportunity to perform genomics and bioinformatics analysis on this family of viruses. Coronaviruses possess the largest genomes (26.4 to 31.7 kb) among all known RNA viruses, with G + C contents varying from 32% to 43%. Variable numbers of small ORFs are present...
Among different coronavirus genera, the receptor-binding S1 subunits of their spike proteins differ in primary, secondary, and tertiary structures. This study identified shared structural topologies (connectivity of secondary structural elements) in S1 domains of different coronavirus genera. The results suggest that coronavirus S1 subunits share a common evolutionary origin but have attained d...
The key enzyme in coronavirus replicase polyprotein processing is the coronavirus main protease, 3CL(pro). The substrate specificities of five coronavirus main proteases, including the prototypic enzymes from the coronavirus groups I, II and III, were characterized. Recombinant main proteases of human coronavirus (HCoV), transmissible gastroenteritis virus (TGEV), feline infectious peritonitis ...
Background and Aim: The novel coronavirus 2019 can lead to a vast range of respiratory complications, from mild to severe, driving to acute respiratory distress syndrome (ARDS). Common symptoms of Covid-19 include fever, fatigue, and dry cough, which can lead to complications, such as gastrointestinal disorders, and liver, cardiac, and renal dysfunctions. Alteration in the hematological markers...
conclusions this study showed that the developed rrt-pcr assays are rapid, reliable, reproducible, specific, sensitive, and simple tools for detection of mers-cov. finally, a kit consisting of two assay signatures and controls was assembled, which can be distributed to public health laboratories in iran to support international mers-cov surveillance and public health response. results the upe a...
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