BACKGROUND AND PURPOSE We measured the temporal evolution of the T2 and diffusion tensor imaging parameters after transient and permanent cerebral middle cerebral artery occlusion (MCAo) in macaques, and compared it to standard histological analysis at the study end point. METHODS Stroke was created in adult male macaques by occluding a middle cerebral artery branch for 3 hours (transient MCA...

Cigarette smoking doubles the risk of dementia and Alzheimer's disease. Various pathophysiological pathways have been proposed to cause such a cognitive decline, but the exact mechanisms remain unclear. Smoking may affect the microstructural integrity of cerebral white matter. Diffusion tensor imaging is known to be sensitive for microstructural changes in cerebral white matter. We therefore cr...

The onset of nonlinear effects in metals, such as plasticity and damage, is strongly influenced by the heterogeneous stress distribution at grain level. This work devoted to studying local fcc polycrystals using FFT-based solvers. In particular, we focus on shear stresses resolved slip systems critical driving force for plastic deformations. Specific orientations with respect load direction are...

BACKGROUND AND PURPOSE Noninvasive radiologic evaluation of glioma can facilitate correct diagnosis and detection of malignant transformation. Although positron-emission tomography is considered valuable in the care of patients with gliomas, (18)F-fluorodeoxyglucose and (11)C-methionine have reportedly shown ambiguous results in terms of grading and prognostication. The present study compared t...

BACKGROUND AND PURPOSE The various stages of multiple sclerosis (MS) are characterized by de- and remyelination as well as by inflammation. Diffusion MR imaging is sensitive to tissue water motion, which might correspond to these pathologic processes. Our purpose was to demonstrate differences in apparent diffusion coefficient (ADC) and diffusion tensor anisotropy in acute and chronic MS plaque...

Teleseismic receiver functions (RFs) from a yearlong broadband seismological experiment in Kamchatka reveal regional variations in the Moho, anisotropy in the supra-slab mantle wedge, and, along the eastern coast, Ps converted phases from the steeply dipping slab. We analyze both radialand transverse-component RFs in bin-averaged epicentral and backazimuthal sweeps, in order to detect Ps moveou...

Geomagnetic field is a one of the candidates for creation of anisotropy in azimuth distribution of extensive air showers over the entered cosmic rays to the atmosphere. Here we present the question: Is there any azimuth anisotropy flux in the upper level of the atmosphere due to the geomagnetic field over the entered cosmic-rays? The obtained answer is: yes. This investigation showed an agreeme...

[1] Flat or shallow subduction is a relatively widespread global occurrence, but the dynamics remain poorly understood. In particular, the interaction between flat slabs and the surrounding mantle flow has yet to be studied in detail. Here we present measurements of seismic anisotropy to investigate mantle flow beneath the Peruvian flat-slab segment, the largest present-day region of flat subdu...

Isotropic earth models are unable to provide uniform fits to the gross Earth normal mode data set or, in many cases, to regional Loveand Rayleigh-wave data. Anisotropic inversion provides a good fit to the data and indicates that the upper 200 km of the mantle is anisotropic. The nature and magnitude of the required anisotropy, moreover, is similar to that found in body wave studies and in stud...