Background: Monosodium glutamate (MSG), used widely in the food industry, is a threat to the public health. We investigated whether the MSG administration depletes non-enzymatic antioxidants, i.e., vitamins C and E in the liver of Wistar albino rats. We also examined the restorative effect of the ethanolic extract of Phyllanthus emblica (P. emblica). Methods: Wistar albino rats (n=42) were ada...

results coincubation of islets with vitamin d (10 nm) and 11.1 mm glucose increased islet insulin release (37.27 ± 3.75 vs. 24.64 ± 2.83 ng/islet/24 hours; p < 0.05), while vitamin d (1 and 10 nm) decreased insulin release in the presence of 16.7 mm glucose (21.14 ± 3.58 and 18.65 ± 3.84 vs. 37.71 ± 4.63 ng/ islet/24 hours; p < 0.05). islets preincubation with vitamin d (1 and 10 nm) increased ...

background: arsenic as an environmental toxicant is able to induced oxidative stress. the present study aimed to evaluate of vitamin c supplementation on the paraoxonase1 (pon1) arylesterase activity (responsible for hydrolysing lipid-peroxides) in rat exposed to arsenic. methods: the study was conducted in the faculty of veterinary medicine, tabriz islamic azad university, tabriz, iran in 2001...

background: hypercholesterolemia is one of the risk factors of cardiovascular diseases. it affects general health and increases cardiovascular mortality rate. diet with high cholesterol increases ldl that, inturn, decrease ldl receptors activity in liver. oxidation of vessel wall lipoproteins increases development of atherosclerosis. several evidences suggest that antioxidants consumption decre...

Using a mitochondria-targeted vitamin E (Mito-Vit-E) in a rat pneumonia-related sepsis model, we examined the role of mitochondrial reactive oxygen species in sepsis-mediated myocardial inflammation and subsequent cardiac contractile dysfunction. Sepsis was produced in adult male Sprague-Dawley rats via intratracheal injection of S. pneumonia (4 × 10(6) colony formation units per rat). A single...

BACKGROUND The role of oxidative stress in endosulfan-induced reproductive toxicity has been implicated. This study was performed to evaluate the possible protective effect of vitamins E and C, against endosulfan-induced reproductive toxicity in rats. METHODS Fifty adult male Sprague-Dawley rats were randomly divided into five groups (n=10 each). The groups included a control receiving vehicl...

BACKGROUND 1,1,2-Trichloroethylene (TCE) is an important organic solvent which is widespread in the environment. Work place exposure to TCE has been associated adverse effects in many organs including kidney. Vitamin E is an antioxidant that can overcome oxidative stress. OBJECTIVES The aim of the present study is to examine the role of vitamin E against destructive effects of TCE on rat kidn...

Nonylphenol and short-chain nonylphenol ethoxylates such as NP2 EO are present in aquatic environment as wastewater contaminants, and their toxic effects on aquatic species have been reported. Apoptosis has been shown to be induced by serum deprivation or copper treatment. To understand the toxicity of nonylphenol diethoxylate, we investigated the effects of NP2 EO on apoptosis induced by serum...

Objective; Tympanosclerosis is a common sequela of tympanoplasty operations causing hearing disability. It is associated with an increased production of free radicals (also known as reactive oxygen species) after trauma. Vitamin E is a scavenger of different free radicals by working as an antioxidant. The aim of the present study was to evaluate the effect of vitamin E-soaked absorbable gelatin...