نتایج جستجو برای: non ulcerogenic

تعداد نتایج: 1317118  

Journal: :Acta pharmaceutica 2008
Mohammad Amir Sadique Akhtar Javed Harish Kumar

Twelve new 4-(1H-indol-3-yl)-6-phenyl-1,2,3,4-tetrahydropyrimidin-2-ones/thiones (7-18) have been synthesized by reacting 1-aryl-3-(1H-indol-3-yl)-2-propen-1-one with urea and thiourea in ethanolic potassium hydroxide. Their structures have been confirmed by IR, 1H NMR and mass spectral data. The compounds were tested for their anti-inflammatory activity. Test results revealed that compounds sh...

2008
Maykel Cruz-Monteagudo Fernanda Borges M. Natália D. S. Cordeiro

Up to now, very few reports have been published concerning the application of multiobjective optimization (MOOP) techniques to quantitative structure–activity relationship (QSAR) studies. However, none reports the optimization of objectives related directly to the desired pharmaceutical profile of the drug. In this work, for the first time, it is proposed a MOOP method based on Derringer’s desi...

Journal: :African journal of traditional, complementary, and alternative medicines : AJTCAM 2012
Seewaboon Sireeratawong Parirat Khonsung Pritsana Piyabhan Urarat Nanna Noppamas Soonthornchareonnon Kanjana Jaijoy

Chantaleela recipe is indicated for relieving fever in Thai traditional folk medicine. In the present study, Chantaleela recipe was investigated for anti-inflammatory, analgesic, antipyretic and anti-ulcerogenic activities. In preliminary investigation Chantaleela recipe was found to exert an inhibitory activity on the acute phase of inflammation as seen in ethyl phenylpropiolate-induced ear ed...

Journal: :International Journal of Basic & Clinical Pharmacology 2018

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