A useful way to summarize the placebo-nocebo theme is to consider the tension and interaction between conviction and responsibility. With the conviction of the mainstream biomedical paradigm prevalent today, it would be tempting to say to Dr. Engel's patient: "That question is nonsense. Cancer pain is not classified as 'male' or 'female.' Pain varies with location in the body and other factors....

OBJECTIVE On the basis of emerging research evidence, this review aims to discuss the importance of the context surrounding the doctor-patient encounter for the success of treatment. DESIGN AND SETTING Discussion paper based on placebo-nocebo and pain studies conducted in the western world. MAIN OUTCOME MEASURES Literature-based theory about impact of communication elements on seriousness o...

UNLABELLED BACKGROUND Patients' expectations of treatment effects may contribute to positive (placebo) and negative (nocebo) outcomes. The effect of patient expectations may be pronounced in subjectively assessed conditions, such as male erectile dysfunction. The aim of this project is to examine the magnitude of expectancy in trials of phosphodiesterase-5 inhibitors. We hypothesize that ran...

The influence of positive or negative expectations on clinical outcomes such as pain relief or motor performance in patients and healthy participants has been extensively investigated for years. Such research promises potential benefit for patient treatment by deliberately using expectations as means to stimulate endogenous regulation processes. Especially regarding recent interest and controve...

Šio straipsnio tikslas − apžvelgti mokslinėje literatūroje vis labiau populiarėjančią nocebo efekto temą ir šio reiškinio įtaką anesteziologijai. Šiomis dienomis gauname daugiau įrodymų, jog pacientų gydymo procese svarbi ne tik tikslingai parinkta taktika, bet tinkamas gydytojo paciento bendradarbiavimas, požiūris į gydymą bei nusiteikimas pasveikti. Anesteziologijoje taikomi metodai procedūro...

Apatient was seen in consultation for intolerance to multiple antihypertensive medications. She presented a list of her experiences, which is summarized in the Table. Although the cough she experienced while taking angiotensinconverting enzyme inhibitors was a typical side effect of this drug class and consistent on rechallenge, this was not the case with her other reported medication reactions...