BACKGROUND Trimethoprim-sulfamethoxazole has consistently been the recommended drug for uncomplicated urinary tract infections in women. Which antibiotics physicians use has implications for patient outcomes, antimicrobial resistance, and costs. METHODS This study was based on a sample survey of practicing physicians participating in the National Ambulatory Medical Care Survey from 1989 throu...

OBJECTIVES Given increasing rates of co-trimoxazole resistance among uropathogens causing acute uncomplicated cystitis, fluoroquinolones, nitrofurantoin and fosfomycin are often considered as alternative empirical therapy. The choice between these drugs should depend in part on whether they are associated with the isolation of drug-resistant microbial flora. We conducted a randomized treatment ...

INTRODUCTION The urinary tract infections, after respiratory infections, are the most common in the community. The knowledge about the prevalence of microbial strains and their antibiotic susceptibility is crucial to establish an effective empirical therapy. The aim of this study was to determine the antibiotic susceptibility patterns of bacterial strains isolated from positive urine cultures p...

This paper describes a case of lung injury attributed to the use of Nitrofurantoin and a review of the relevant literature. An 88-year-old woman was admitted to the floor for the evaluation of recent symptoms of dyspnea, fatigue and productive cough. She was initiated on nitrofurantoin 300 mg per day for the treatment of a urinary tract infection 3 days earlier. Upon examination, chest ausculta...

Objective: The Urinary tract is one of the most common source for life threatening infection. A broad range of organisms may be isolated. Various antibiotics are used for the treatment but rising resistance among pathogenic organisms is one major concern in choosing effective treatment option. The main objective of the study was to check the efficacy and safety of nitrofurantoin (100 mg BD dose...