There were worries that the COVID-19 pandemic could result in a shortage of supplies some drugs. We aimed to analyze if resulted availability drop different cardiodiabetological medicaments. Special attention was put combined therapies and investigate general these Data obtained from Polish startup company GdziePoLek regarding 121 cardiodiabetolocigal drugs divided into 23 separate categories p...

The effect of morphine on the binding of 3H-nitrendipine was studied in rat hippocampal preparations. Treatment of slices with morphine followed by the preparation of membrane fractions revealed the presence of low affinity binding sites. The effect of morphine was antagonized by naloxone. The effect was not observed when the membrane fraction was incubated with morphine. These results suggest ...

PURPOSE Indapamide, a non-thiazide antihypertensive diuretic agent, has been widely coadministered with other classes of antihypertensive agents to reach target systolic blood pressure. Indapamide is extensively metabolized by cytochromes P450. Interaction of indapamide and other antihypertensive drugs are unknown. We investigated the effects of other antihypertensive drugs on the metabolism an...