BACKGROUND Occupational noise induced hearing loss (NIHL) occurs among workers exposed to excessive amounts of noise for long durations. The average level of noise in some locations at Jomo Kenyatta International Airport (JKIA) was above the safe limit of 85dB hence workers were thought to be at risk. OBJECTIVE To determine the occurrence and socio demographic attributes for NIHL at JKIA. D...

BACKGROUND A reduction in cochlear blood flow plays an essential role in noise-induced hearing loss (NIHL). The timely regulation of cochlear perfusion determines the progression and prognosis of NIHL. Hydrogen sulfide (H(2)S) has attracted increasing interest as a vasodilator in cardiovascular systems. This study identified the role of H(2)S in cochlear blood flow regulation and noise protecti...

MYH14 is a member of the myosin family, which has been implicated in many motile processes such as ion-channel gating, organelle translocation, and the cytoskeleton rearrangement. Mutations in MYH14 lead to a DFNA4-type hearing impairment. Further evidence also shows that MYH14 is a candidate noise-induced hearing loss (NIHL) susceptible gene. However, the specific roles of MYH14 in auditory fu...

OBJECTIVE Oxidative damage is a critical role which involves hearing loss induced by impulse noise. That exogenous antioxidant agents reduce noise induced hearing loss (NIHL) has been well demonstrated in both animal studies and clinical practices. Choosing a stronger and more effective antioxidant is very important for treatment of NIHL. Vitamin E, α-lipoic acid, and radix astragali are the mo...

Extracellular signal-regulated kinase (ERK) is a member of the family of mitogen-activated protein kinases (MAPKs) and coordinately regulates a multitude of cellular processes. In response to a variety of extracellular stimuli, phosphorylation of both threonine and tyrosine residues activates ERK. Recent evidence indicates that ERK is activated in response to cellular stress such as acoustic tr...

background: noise-induced hearing loss (nihl) is a common, irreversible occupational disease. statins have recently been proposed to prevent nihl. objective: to assess the effect of atorvastatin for the prevention of nihl in rats. methods: in this experimental study, forty 2–3-month-old wistar male rats were divided into 5 groups of 8 animals. 3 groups of rats received atorvastatin at doses of ...

Ross et al. [1] compared hearing loss in divers and offshore workers and concluded that current Health & Safety Executive (HSE) guidance on the assessment of audiograms is ‘in error’ and ‘inadequate’. Grading the sum of hearing thresholds at 1, 2, 3, 4 and 6 kHz using the HSE ‘age-adjusted norm’ values [2], they found that the HSE scheme missed referring roughly half of people thought to have s...

Personal audio systems (PAS) use is a major risk factor for noise-induced hearing loss (NIHL). PAS include content device and earbuds or headphones listening to personal without disturbing others. are inherently unsafe because their design exposes users high sound pressure levels. at about 4-times greater of developing NIHL than non-users, with reported in as young 9. The greatest > 1 hour dail...

Noise measurements and questionnaire inquiries were carried out for 124 workers of a rolling stock plant to develop a hearing conservation program. On the basis of that data, the risk of noise-induced hearing loss (NIHL) was evaluated. Additionally, the workers' hearing ability was assessed with the (modified) Amsterdam inventory for auditory disability and handicap, (m)AIADH. The workers had b...

Acoustic trauma is one of the major causes of hearing loss and tinnitus, particularly in industrial environments. Noise-induced hearing loss (NIHL) results in direct mechanical damage as well as in indirect metabolic processes. Metabolic disorders have multiple origins: ionic, ischemic, excitotoxic and production of cochlear free radicals causing cell death, due to necrosis or apoptosis. The ef...